TITLE

Clarithromycin, lansoprazole, and metronidazole eradicated H. pylori infection in chronic renal insufficiency

PUB. DATE
March 2004
SOURCE
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p40
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article examines if triple therapy consisting of clarithromycin, lansoprazole, and metronidazole (CLM) is more effective than one consisting of clarithromycin, lansoprazole, and a reduced dosage of amoxicillin (CLA) for eradicating Helicobacter pylori in patients with dyspepsia and chronic renal insufficiency. 88 patients with dyspepsia who had chronic renal insufficiency and H. pylori infection were analysed in a hospital. 44 patients each were allocated to CLM or CLA and amoxicillin 750, twice daily for 1 week. The rates of successful H. pylori eradication and complete drug compliance were greater in the CLM group than in the CLA group.
ACCESSION #
12597128

 

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