Ximelagatran was noninferior to warfarin in preventing stroke and systemic embolism in atrial fibrillation

March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p39
Academic Journal
The article analyses if ximelagatran is noninferior to warfarin in preventing stroke and systemic embolism in patients with atrial fibrillation (AF) at risk for ischemic stroke. 3410 patients at 18 years of age who had nonvalvular AF and less than or equal to 1 additional risk factor for stroke treatment for hypertension but blood pressure were examined. Secondary outcomes included composite endpoints of major and minor bleeding, ischemic stroke, and systemic embolism. Ximelagatran was not inferior to warfarin for stroke and systemic embolism, or for the secondary outcomes.


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