Conventional-intensity was more effective than low-intensity warfarin therapy for preventing recurrent venous thromboembolism

March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p37
Academic Journal
The article examines if low-intensity warfarin therapy is as effective as conventional-intensity warfarin therapy for the long-term prevention of recurrent venous thromboembolism (VTE) in patients with unprovoked VTE. 738 patients with less than 1 episode of unprovoked VTE, which is defined as objectively confirmed, symptomatic, proximal deep venous thrombosis or pulmonary embolism that occurred in the absence of a major risk factor for thrombosis, were analyzed. It was confirmed that in patients with unprovoked venous thromboembolism conventional-intensity warfarin therapy was more effective than low-intensity warfarin therapy for long-term prevention of recurrent VTE.


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