Review: Adjuvant corticosteroid therapy reduces death, hearing loss, and neurologic sequelae in bacterial meningitis

March 2004
ACP Journal Club;Mar/Apr2004, Vol. 140 Issue 2, p34
Academic Journal
The article focuses on a study conducted to examine if adjuvant corticosteroid therapy more effective than placebo for reducing mortality, hearing loss, and neurologic sequelae in children and adults with acute bacterial meningitis (ABM). Studies in any language were selected if they were randomized controlled trials that compared any type of corticosteroid therapy adjuvant to antibiotics with placebo in patients with ABM and recorded case fatality rates. It was found that in children and adults with acute bacterial meningitis, adjuvant corticosteroid therapy reduces mortality, hearing loss, and longterm neurologic sequelae.


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