Granular Cell Tumor of the Breast

Montagnese, Miguel D.; Roshong-Denk, Stacie; Zaher, Aiman; Mohamed, Iman; Staren, Edgar D.
January 2004
American Surgeon;Jan2004, Vol. 70 Issue 1, p52
Academic Journal
Granular cell tumors (GCT) are uncommon, usually benign, neoplasms that are thought to derive from Schwann cells of the peripheral nerves. They can originate anywhere in the body but are most frequently found in the head and neck, particularly in the oral cavity. When they are located in the breast, as may occur in 5-8 per cent of cases, the clinical and pathologic appearance is similar to that of a malignant tumor. Immunohistochemical analysis, including reactivity for periodic acid-Schiff, CD68, and $100 and negative reactivity for cytokeratin, is required for definitive diagnosis. Awareness of this tumor's unique characteristics might aid in differentiating it from the more common malignant tumors of the breast.


Related Articles

  • A Neonate With Neck Swelling and Fever. Migally, Karl; Hart, Catherine; Klein, Melissa // Clinical Pediatrics;Mar2013, Vol. 52 Issue 3, p275 

    The article discusses about how a 3 week old patient with neck swelling diagnosed, the symptoms looked in for and how it was concluded that the patient was suffering with branchial cleft sinus. The article further explains that branchial anomalies in form of sinus and fistula mostly found in...

  • Emerging Concepts in Head and Neck Squamous Cell Carcinoma. Prystowsky, Michael B. // Archives of Pathology & Laboratory Medicine;Nov2015, Vol. 139 Issue 11, p1332 

    An introduction is presented in which the editor discusses reports within the issue on topics including the growing understanding of the causative agents of head and neck squamous cell carcinoma (HNSCC) and the epigenetic differences between various types of squamous cell carcinoma (SCC).

  • Sublingual epidermoid cyst in a neonate. Oginni, Fadekemi Olufunmilayo; Oladejo, Taoreed; Braimah, Ramat Oyebunmi; Adenekan, Anthony Taiwo // Annals of Maxillofacial Surgery;Jan-Jun2014, Vol. 4 Issue 1, p96 

    Epidermoid cysts (EC) in the head and neck region could be considered a rare condition representing only 6.9% of all ECs occurring in the body. They occur rarely in children and neonates. We present a case of sublingual EC in a Nigerian neonate.

  • Distinctive Soft Tissue Tumors of the Head and Neck. Fletcher, Christopher D. M. // Modern Pathology;Mar2002, Vol. 15 Issue 3, p324 

    Among soft tissue tumors as a whole, those in the head and neck region are relatively uncommon, and the proportion of all soft tissue sarcomas that arise in this region is ≤5-10% (although this figure is higher in children). With the exceptions of nasopharyngeal angiofibroma and sinonasal...

  • Review rates of head and neck cancer pathology vary widely. Hawkes, Nigel // BMJ: British Medical Journal;9/21/2013, Vol. 347 Issue 7925, p5 

    The article discusses a report published on the Web site of National Health Service (NHS) Choices which found that the review rates of head and neck cancer pathology vary widely between hospitals in Great Britain.

  • A Century of Progress in Head & Neck Cancer. Palma, Gina L. // Annals of Otology, Rhinology & Laryngology;Feb2016, Vol. 125 Issue 2, p177 

    No abstract available.

  • Subglottic thyroglossal duct cyst: A rare intralaryngeal presentation. Kurien, Regi; Michael, Rajiv // ENT: Ear, Nose & Throat Journal;Jul2012, Vol. 91 Issue 7, pE15 

    Thyroglossal duct cysts are common midline neck swellings that can present at any site along their migratory pathway. They are frequently situated just below the hyoid bone. Extension to the subglottic area is very rare; such an unusual presentation can complicate the diagnosis of a thyroglossal...

  • Neck Masses in Children. Eapen, Amy; Kamat, Deepak // Clinical Pediatrics;Oct2014, Vol. 53 Issue 11, p1027 

    The article discuses the etiologies and an assessment of neck masses in children. Topics discussed include the cause for neck masses such as malignancies and congenital anomalies, the importance of inquiring about radiation exposure to the head and neck areas since it is the common cause for...

  • Commentary. Laskar, Sarbani Ghosh; Chatterjee, Abhishek // Indian Journal of Palliative Care;Sep-Dec2015, Vol. 21 Issue 3, p296 

    A letter to the editor is presented in response to the article "Nutritional Assessment and Dietary Intervention in HNCA Patients" by A. Bhattacharjee et al.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics