TITLE

Granular Cell Tumor of the Breast

AUTHOR(S)
Montagnese, Miguel D.; Roshong-Denk, Stacie; Zaher, Aiman; Mohamed, Iman; Staren, Edgar D.
PUB. DATE
January 2004
SOURCE
American Surgeon;Jan2004, Vol. 70 Issue 1, p52
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Granular cell tumors (GCT) are uncommon, usually benign, neoplasms that are thought to derive from Schwann cells of the peripheral nerves. They can originate anywhere in the body but are most frequently found in the head and neck, particularly in the oral cavity. When they are located in the breast, as may occur in 5-8 per cent of cases, the clinical and pathologic appearance is similar to that of a malignant tumor. Immunohistochemical analysis, including reactivity for periodic acid-Schiff, CD68, and $100 and negative reactivity for cytokeratin, is required for definitive diagnosis. Awareness of this tumor's unique characteristics might aid in differentiating it from the more common malignant tumors of the breast.
ACCESSION #
12536187

 

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