TITLE

THYMUS-DEPENDENT LYMPHOCYTES IN LYMPHOPROLIFERATIVE DISORDERS OF THE SKIN (SÉZARY SYNDROME AND MYCOSIS FUNGOIDES)

AUTHOR(S)
Zucker-Franklin, Dorothea
PUB. DATE
September 1976
SOURCE
Journal of Investigative Dermatology;Sep76, Vol. 67 Issue 3, p412
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Practically all circulating blood cells migrate through the skin. This process is accelerated during the acute inflammatory reaction where the stimuli for diapedesis and chemotaxis of granulocytes and macrophages are reasonably well understood. Since it is generally believed that lymphocytes seen in the skin are of hematogenous rather than of local origin, the distribution of cells infiltrating the skin may reflect the percentages present in circulating blood. It is dangerous to assume that in all pathologic states tissue lymphocytes have the same distribution as those in the blood.
ACCESSION #
12514715

 

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