Dvorak, Harold F.; Mihm Jr., Martin C.; Dvorak, Ann M.
September 1976
Journal of Investigative Dermatology;Sep76, Vol. 67 Issue 3, p391
Academic Journal
A first essential step towards an understanding of any inflammatory process in man or experimental animals is an adequate understanding of its morphology. Morphology is required to appreciate the various components comprising the process, including the various types of cells involved. The purpose of this presentation is to provide for nonmorphologists a brief summary of the morphology of delayed-type hypersensitivity reactions as they occur in man and to provide recent ultrastructural evidence concerning the function of basophilic leukocytes in cell-mediated hypersensitivity.


Related Articles

  • Delayed-Type Hypersensitivity (DTH). Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p192 

    The article offers information about delayed-type hypersensitivity (DTH). It refers to a form of cell mediated immune reaction to an antigen or allergen that appears only after 24-48 hours. This delayed reaction is caused by the activation of mast cells and basophils. It can be separated into...

  • Itching 9-5. Cox, Margaret // Occupational Health;Sep2004, Vol. 56 Issue 9, p18 

    Presents information on contact dermatitis. Difference between irritant contact dermatitis and allergic contact dermatitis; Examples of irritants; Ways to reduce contact dermatitis with potential irritants and sensitizers.

  • Patch test results in patients with allergic contact dermatitis in the Podlasie region. Reduta, Teresa; Bacharewicz, Joanna; Pawłoś, Anna // Advances in Dermatology & Allergology / Postepy Dermatologii i A;Dec2013, Vol. 30 Issue 6, p350 

    Introduction: The aim of the study was to provide current data on the incidence of allergy to various contact allergens in patients with allergic contact eczema and the analysis of selected socio-demographic data of the patients. Material and methods: The study included 1532 patients (1010 women...

  • Lichenoid Tissue Reaction Induced by Local Transfer of Ia-Reactive T-Cell Clones. Shiohara, Tetsuo; Moriya, Noriko; Tsuchiya, Keiko; Nagashima, Masaji; Narimatsu, Hisashi // Journal of Investigative Dermatology;Jul86, Vol. 87 Issue 1, p33 

    Epidermal basal cell damage in lichenoid tissue reactions (LTR) is considered to be the result of immunologic injury. In this study, we propose that LTR may be caused by local activation of Ia-reactive T cells. We have established allo-Iak-reactive helper T-cell clones and examined their...

  • Delayed Type IV Hypersensitivity. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p192 

    The article offers information on delayed type IV hypersensitivity. It refers to an cell-mediated immune response to repeated exposure to antigen. Treatment requires the activation of antigen-specific specific T cells which produce cytokines. It is linked with chronic beryllium disease.

  • MEDIATORS OF CELLULAR IMMUNITY, THEIR NATURE AND ASSAY. Rocklin, Ross E. // Journal of Investigative Dermatology;Sep76, Vol. 67 Issue 3, p372 

    There is ample evidence from adoptive transfer experiments that the actual number of antigen reactive cells present at the site of a delayed hypersensitivity skin reaction is very small. A number of in vitro models have been developed which permit isolation of cells potentially involved in the...

  • Allergic contact dermatitis of the auricle. Wilkinson, Eric P.; Fayad, Jose N. // ENT: Ear, Nose & Throat Journal;May2007, Vol. 86 Issue 5, p260 

    The article presents the case of a 37-year-old man who was diagnosed with allergic contact dermatitis of the auricle. It says that the patient started experiencing auricular erythema following a left tympanoplasty through a postauricular approach. Also noted is that the skin inflammation...

  • Pimecrolimus offers effective, safe option for hand dermatitis.  // Dermatology Times;Jun2004, Vol. 25 Issue 6, p39 

    A recent pilot study suggests Elidel could provide a safe effective option for treating chronic hand dermatitis and, by extension, chronic cumulative irritant contact dermatitis. In the muticenter randomized, vehicle-controlled study researchers treated 294 patients for up to three weeks with...

  • Managing ACD requires education, effort. Jesitus, John // Dermatology Times;Jun2004, Vol. 25 Issue 6, p43 

    Most sufferers of allergic contact dermatitis (ACD) also suffer from a misunderstanding of the condition. "People seem to think that if you're allergic to something, as soon as it comes into contact with you. you're going to break out," says Sophie M. Worobec, associate professor of clinical...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics