Rocklin, Ross E.
September 1976
Journal of Investigative Dermatology;Sep76, Vol. 67 Issue 3, p372
Academic Journal
There is ample evidence from adoptive transfer experiments that the actual number of antigen reactive cells present at the site of a delayed hypersensitivity skin reaction is very small. A number of in vitro models have been developed which permit isolation of cells potentially involved in the cell-mediated immune reaction and study of their function and interactions. By virtue of their biologic effects, one can see how they may play a role in vivo in the expression of CMI reactions in the skin, in resistance to infection by intracellular facultative organisms, and inflammation.


Related Articles

  • Itching 9-5. Cox, Margaret // Occupational Health;Sep2004, Vol. 56 Issue 9, p18 

    Presents information on contact dermatitis. Difference between irritant contact dermatitis and allergic contact dermatitis; Examples of irritants; Ways to reduce contact dermatitis with potential irritants and sensitizers.

  • Patch test results in patients with allergic contact dermatitis in the Podlasie region. Reduta, Teresa; Bacharewicz, Joanna; Pawłoś, Anna // Advances in Dermatology & Allergology / Postepy Dermatologii i A;Dec2013, Vol. 30 Issue 6, p350 

    Introduction: The aim of the study was to provide current data on the incidence of allergy to various contact allergens in patients with allergic contact eczema and the analysis of selected socio-demographic data of the patients. Material and methods: The study included 1532 patients (1010 women...

  • Allerjik Kontakt Dermatitler. Önder, Meltem // Archives of the Turkish Dermatology & Venerology / Turkderm;2009, Vol. 43 Issue 1, p3 

    Allergic contact dermatitis is the delayed type hypersensitivity reaction to exogenous agents. Allergic contact dermatitis may clinically present acutely after allergen exposure and initial sensitization in a previously sensitized individual. Acute phase is characterized by erythematous, scaly...

  • Allergic contact dermatitis of the auricle. Wilkinson, Eric P.; Fayad, Jose N. // ENT: Ear, Nose & Throat Journal;May2007, Vol. 86 Issue 5, p260 

    The article presents the case of a 37-year-old man who was diagnosed with allergic contact dermatitis of the auricle. It says that the patient started experiencing auricular erythema following a left tympanoplasty through a postauricular approach. Also noted is that the skin inflammation...

  • Managing ACD requires education, effort. Jesitus, John // Dermatology Times;Jun2004, Vol. 25 Issue 6, p43 

    Most sufferers of allergic contact dermatitis (ACD) also suffer from a misunderstanding of the condition. "People seem to think that if you're allergic to something, as soon as it comes into contact with you. you're going to break out," says Sophie M. Worobec, associate professor of clinical...

  • Suppression of Allergic Contact Dermatitis by α-L-fucose. Hasegawa, Shoji; Baba, Toru; Hori, Yoshiaki // Journal of Investigative Dermatology;Sep80, Vol. 75 Issue 3, p284 

    We observed that L-fucose could suppress the skin reaction of allergic contact dermatitis induced by dinitrochlorobenzene. This observation was ascertained by histological examination as well as by visual inspection. The degrees of the acanthosis and the spongiosis were significantly slighter in...

  • Neuropeptides Enhance Irritant and Allergic Contact Dermatitis. Gutwald, Johannes; Goebeler, Matthias; Sorg, Clemens // Journal of Investigative Dermatology;May91, Vol. 96 Issue 5, p695 

    It is supposed that neuropeptides participate in the regulation of delayed-type hypersensitivity (DTH) reactions. However, their function in this kind of immune response is not known presently. Therefore, in vivo studies were initiated to test the effect on allergic (ACD) and irritant contact...

  • Allergic Contact Dermatitis. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p13 

    A definition of allergic contact dermatitis is presented. It is described as a delayed inflammatory reaction on the skin seen in type IV hypersensitivity, resulting from allergic sensitization.

  • Delayed-Type Hypersensitivity. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p192 

    The article offers information about delayed-type hypersensitivity (DTH). It refers to an allergic immune reaction and is also called cell-mediated hypersensitivity. It has three types: contact hypersensitivity, tuberculin-type reaction and granulomatous hypersensitivity. The characteristics and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics