Jordon, Robert E.
September 1976
Journal of Investigative Dermatology;Sep76, Vol. 67 Issue 3, p366
Academic Journal
Pemphigus and bullous pemphigoid are members of the chronic nonhereditary blistering skin diseases of man. The characteristic histopathology--intraepidermal bulla formation with loss of cohesion of the epidermal cells--is diagnostic of pemphigus. Bullous pemphigoid, a disease with a much better prognosis, affects chiefly the elderly patient. It is characterized by large tense blisters involving primarily the intertriginous areas. With the use of immunofluorescent methods, distinct immune responses and staining patterns have been recognized in pemphigus and bullous pemphigoid.


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