Agnello, Vincent; Gabriel Jr., Alexandre; Tai, Mindy
September 1976
Journal of Investigative Dermatology;Sep76, Vol. 67 Issue 3, p339
Academic Journal
In most human diseases where immune complexes have been implicated in the pathologic process, the antigen or antigens involved are unknown. Complexes of unknown composition have been detected in pathologic fluids from patients with dermatitis herpetiformis, pemphigus, leprosy, schistosomiasis and most recently, melanoma. The cellular methods utilize various cell receptors or activities specific for complexed globulin. There are, however, a number of methods using biologic reagents which react specifically with some types of antibody complexes and have been utilized in immune complex detection assays.


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