Successful CABG in a patient with paroxysmal nocturnal hemoglobinuria

Naito, Yuji; Nakajima, Masato; Inoue, Hidenori; Tsuchiya, Koji
March 2004
European Journal of Cardio-Thoracic Surgery;Mar2004, Vol. 25 Issue 3, p468
Academic Journal
Paroxysmal nocturnal hemoglobinuria (PNH) is an uncommon acquired disorder of blood cells characterized by intravascular hemolysis due to an inordinate sensitivity to complement-mediated membrane damage. This report documents coronary artery revascularization in a patient with PNH, which has not been described in the literature so far. We used the on-pump procedure in the present patient and successfully performed revascularization by taking prophylactic measures against hemolysis.


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