TITLE

Diabetes and Oral Tumors in Hungary

AUTHOR(S)
Ujpál, Márta; Matos, Orsolya; Bíbok, György; Somogyi, Anikó; Szabó, György; Suba, Zsuzsanna
PUB. DATE
March 2004
SOURCE
Diabetes Care;Mar2004, Vol. 27 Issue 3, p770
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Numerous publications have already demonstrated that diabetes is a risk factor for the development of periodontal diseases and various inflammatory lesions in the oral mucosa. A possible correlation between diabetes and oral premalignancies and tumors was examined in this study, as no literature data are available concerning this problem. Benign tumors were found in 14.5% and precancerous lesions in 8% of diabetic patients. In the control group these values were significantly lower, at 6.4 and 3.2%, respectively (P > 0.01). Earlier Hungarian screening studies indicated similar frequency of these lesions in the general population. The proportion of oral cavity lesions was higher among diabetic patients compared with that of the control patients. In the oral cancer patient group, diabetes was present in 14.6% and an elevated blood glucose level in 9.7%. These values are significantly higher than those for the tumor-free control group (P < 0.01). The gingival and labial tumor location was significantly more frequent among diabetic cancer patients than in the nondiabetic group (P < 0.01). The combination of diabetes and smoking means a higher risk for oral pre-cancerous lesions and malignancies. Diabetes may be a risk factor for oral pre-malignancies and tumors.
ACCESSION #
12421003

 

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