Accuracy of the GlucoWatch G2 Biographer and the Continuous Glucose Monitoring System During Hypoglycemia

Buckingham, Bruce A.; Wilson, Darrell M.; Bucksa, Jean M.; Kunselman, Elizabeth L.; Tamborlane, William V.; Doyle, Elizabeth A.
March 2004
Diabetes Care;Mar2004, Vol. 27 Issue 3, p722
Academic Journal
The goal of this study was to assess the accuracy of the GlucoWatch G Biographer (GW2B) and the continuous glucose monitoring system (CGMS) during hypoglyce mia m children and adolescents with type 1 diabetes. During hypoglycemia, the median absolute difference between the 192 GW2 reference glucose pairs was 26 mg/dl and between the 401 CGMS reference glucose pairs was mg/dl with 31 and 42%, respectively, of the sensor values within 15 mg/dl of the reference glucose. Sensitivity to detect hypoglycemia when the GW2B alarm level was set to 60 mg/dl was 23 % with a false false-rate of 51%. Analyses suggested that modified CGMS sensors that became available in November 2002 might be more accurate than the original CGMS sensors (media absolute difference 15 vs. 20 mg/dl). These data show that the GW2B and the CGMS do not reliably detect hypoglycemia. Both of these devices perform better at higher glucose levels, suggesting they may be more useful in reducing HbA1c levels than in detecting hypoglycemia.


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