TITLE

In vitro assessment of the unloading and perfusion capacities of the PUCA II and the IABP

AUTHOR(S)
Vandenberghe, Stijn; Segers, Patrick; Josemans, Hans; Van Loon, Jan-Paul; Rakhorts, Gerhard; Verdonck, Pascal
PUB. DATE
January 2004
SOURCE
Perfusion;Jan2004, Vol. 19 Issue 1, p25
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The PUCA II pump is a minimally invasive intra-arterial left ventricular assist device that can be used as an alternative for the intra-aortic balloon pump (IABP). In this study, we assessed the cardiac unloading and organ perfusion capacities of both PUCA II and IABP in an in vitro set up, consisting of a heart simulator and a silicone arterial tree, mimicking anatomical geometry and flow distribution. The IABP was positioned in the descending aorta, while the PUCA II was tested both in 'trans-aortic' and 'abdominal' positions. All devices were driven by the same Arrow AutoCat IABP driver at different pump rates. Apart from flow, arterial pressure and pulse pressure, we also calculated haemodynamic indices for myocardial oxygen supply and demand. The 'abdominal' PUCA II assist and the IABP both provide mild unloading of the heart, and a limited improvement of arterial pressure and flow. The 'trans-aortic' PUCA II assist greatly enhances flow and pressure, but does not unload the heart properly in the tested configuration.
ACCESSION #
12408543

 

Related Articles

  • In viva evaluation of tissue microflow under combined therapy with extracorporeal life support and intra-aortic balloon counterpulsation. JUNG, C.; LAUTEN, A.; ROEDIGER, C.; FRITZENWANGER, M.; SCHUMM, J.; FIGULLA, H. R.; FERRARI, M. // Anaesthesia & Intensive Care;Sep2009, Vol. 37 Issue 5, p833 

    The article evaluates the microcirculation in a patient with severe cardiogenic shock supported by extracorporeal membrane oxygenation (ECMO) and intra-aortic balloon pump (IABP) counterpulsation using a sidestream darkfield intravitalmicroscope. A prognostic role may be played by...

  • Effects of 1:1, 1:2 or 1:3 intra-aortic balloon counterpulsation/heart support on coronary haemodynamics and cardiac contractile efficiency in an animal model of myocardial ischaemia/reperfusion†. Gelsomino, Sandro; Renzulli, Attilio; Rubino, Antonino S.; Romano, Salvatore Mario; Lucà, Fabiana; Valente, Serafina; Gensini, Gian Franco; Lorusso, Roberto // European Journal of Cardio-Thoracic Surgery;Aug2012, Vol. 42 Issue 2, p325 

    OBJECTIVES The effects of operational modes of intra-aortic balloon pumping (IABP) on coronary haemodynamics and oxygen delivery/demand ratio are unknown and were investigated in an experimental model of myocardial ischaemia reperfusion. METHODS Healthy swine (n = 24) underwent 120-minute...

  • ESC notebook.  // Medical Device Daily;8/29/2012, Vol. 16 Issue 168, p2 

    The article reports on the results of the intra-aortic balloon counterpulsation therapy multicenter IABP-SHOCK II clinical trial in patients with acute myocardial infarction (AMI) who were in cardiogenic shock and undergoing early revascularization.

  • NEW PRODUCTS. Zeidel, Nancy // RN;Aug2000, Vol. 63 Issue 8, p86 

    Features various medical equipment. Defibrillator from Medtronic Physio-Control Corp.; Vasomedical Inc.'s enhanced external counterpulsation system; Altimate Medical Inc.'s EasyStand 5000 Youth, a device that helps handicapped adolescent patients move from a sitting to a standing position.

  • Abiomed wins CE marking for iPulse console platform, IAB.  // Biomedical Business & Technology;Feb2007, Vol. 30 Issue 2, p16 

    The article reports on the CE mark received by medical device maker Abiomed for its intra-aortic balloon and iPulse console platform. The mark allows the products to be sold in all European Union countries. Information on the products is offered. The company expects to begin shipping its iPulse...

  • Intra-aortic balloon pumping reduces the increased arterial load caused by acute cardiac depression, modifying central and peripheral load determinants in a time- and flow-related way. Bia, Daniel; Cabrera-Fischer, Edmundo; Zócalo, Yanina; Armentano, Ricardo // Heart & Vessels;Sep2012, Vol. 27 Issue 5, p517 

    The mechanisms that explain intra-aortic balloon pumping (IABP) effects are not completely understood, and attributing them only to pressure-associated changes in cardiac function would be an oversimplification. Since IABP modifies the aortic and systemic blood-flow pattern, flow-related effects...

  • Abiomed's Impella approved as circulatory support tool. Yoffee, Lynn // Medical Device Daily;6/3/2008, Vol. 12 Issue 106, p1 

    The article reports on the 510(k) clearance granted by the U.S. Food and Drug Administration (FDA) in June 2008 to Abiomed for its Impella 2.5 cardiac assist device for the cath lab that interventionalists can use to increase blood flow to the heart muscle and vital organs. Intra-aortic balloon...

  • Intraaortic Balloon Pump Counterpulsation and Cerebral Autoregulation: an observational study. Bellapart, Judith; Geng, Shureng; Dunster, Kimble; Timms, Daniel; Barnett, Adrian G.; Boots, Rob; Fraser, John F. // BMC Anesthesiology;2010, Vol. 10, Special section p1 

    Background: The use of Intra-aortic counterpulsation is a well established supportive therapy for patients in cardiac failure or after cardiac surgery. Blood pressure variations induced by counterpulsation are transmitted to the cerebral arteries, challenging cerebral autoregulatory mechanisms...

  • Intra-aortic balloon pumping increases renal blood flow in patients with low left ventricular ejection fraction. Sloth, E.; Sprogøe, P.; Lindskov, C.; Hørlyck, A.; Solvig, J.; Jakobsen, C. J. // Perfusion;Jul2008, Vol. 23 Issue 4, p223 

    Intra-aortic balloon pumping (IABP) has, for decades, been one of the key treatment modalities following impaired cardiac function after cardiac surgery. IABP increases cardiac output, decreases oxygen consumption of the heart and relieves the left ventricle. However, a number of complications...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics