Davis, Mark Denis P.
March 2004
Mayo Clinic Proceedings;Mar2004, Vol. 79 Issue 3, p298
Academic Journal
Erythromelalgia is a term that describes the clinical syndrome of red, hot extremities. This rare disorder has been described and characterized in patients seen at the Mayo Clinic in Rochester, Minnesota, for many decades. The lower extremities are involved more frequently than are the upper extremities, and involvement is often symmetrical. Symptoms can be intermittent or, more rarely, constant. The pain can be severe and debilitating; patients attempt to cool the affected areas. Primary and secondary forms of erythromelalgia have been described. Polycythemia vera and other myeloproliferative disorders may underlie the secondary form.


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