Current Literature Gap Junctions in Epileptogenesis: Chicken or Egg?

Benardo, Larry S.
March 2004
Epilepsy Currents;Mar/Apr2004, Vol. 4 Issue 2, p80
Academic Journal
Comments on the study "Epileptiform Activity in Hippocampal Slice Cultures Exposed Chronically to Bicuculline: Increased Gap-Junctional Function and Expression," by M. Samoilova, J. Li, M. R. Pelletier, K. Wentlandt, Y. Adamchik, C. C. Naus and P. L. Carlen, which examined the influence of additional gap junctions and paroxysmal discharge on epileptogenesis. Genetic transcription of messenger RNA during epileptiform activity; Analysis of additional gap junctions in bicuculline-exposed hippocampal slices; Physiological significance of gap junctions.


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