Targeting thrombolysis in pulmonary embolism

March 2004
CMAJ: Canadian Medical Association Journal;3/2/2004, Vol. 170 Issue 5, p784
Academic Journal
Discusses the use of thrombolytic drugs in treating pulmonary embolism. Complications of using systematic thrombolytic drugs; Result of coupling an antibody that was specific in vascular endothelium found in pulmonary tissues to a thrombolytic drug called urokinase; Difference of the conjugate from standard drugs.


Related Articles

  • THROMBOLYTIC THERAPY: DIFFERENCES BETWEEN STREPTOKINASE AND UROKINASE. Bell, William R. // Vascular Surgery;Nov/Dec1977, Vol. 11 Issue 6, p378 

    Compares the relative potency of streptokinase and urokinase as agents for thrombolytic therapy in patients with pulmonary emboli. Therapeutic regimens of streptokinase and urokinase; Biochemical properties of streptokinase and urokinase; Assessment of the therapeutic improvement after the...

  • Thrombolytics / Anticoagulents.  // Cardiovascular Pharmacology Manual;2008, p26 

    The article presents information about several thrombolytics and anticoagulents, they include urokinase, streptokinase and alteplase. Some of the diseases treated by these anticoagulents are myocardial infarction and massive pulmonary embolism. Their adverse effects include bleeding, anaphylaxis...

  • Pulmonary Embolism.  // Current Medical Literature: Respiratory Medicine;2009, Vol. 23 Issue 3, p68 

    The article summarizes studies related to pulmonary embolism. In the study "Outpatient Treatment and Early Discharge of Symptomatic Pulmonary Embolism: A Systematic Review," by A. Squizzato et al., the authors determined the evidence supporting the outpatient management of symptomatic pulmonary...

  • Re-introduction of urokinase.  // WHO Drug Information;2002, Vol. 16 Issue 3, p232 

    Reports on the U.S. Food and Drug Administration's reintroduction of urokinase onto the market. Indication of the drug solely for the treatment of pulmonary embolism; Labeling information of the drug.

  • THROMBOLYTIC THERAPY FOR PULMONARY EMBOLISM. Katchan, Brian M. // Canadian Journal of Surgery;Dec2000, Vol. 43 Issue 6, p411 

    Discusses the treatment of acute pulmonary embolism using thrombolytic therapy. Evidence on the effectiveness of thrombolytic agents to dissolve blood clot than heparin; Risk of major hemorrhage related to the use of thrombolytic agents; Acute right ventricular dysfunction as an indication for...

  • Thrombolytic Therapy in Thrombosis: A National Institutes of Health Consensus Development Conference. Sherry, Sol; Bell, William R.; Duckert, F.H.; Fletcher, Anthony P.; Gurewich, Victor; Long, David M.; Marder, Victor J.; Roberts, Harold; Salzman, Edwin W.; Sasahara, Arthur; Verstraete, Marc // Annals of Internal Medicine;Jul80 Part 1, Vol. 93 Issue 1, p141 

    Editorial. Presents the consensus reached by a National Institutes of Health during a 1980 conference on thrombolytic therapy in thrombosis. Benefits for the use of thrombolytic therapy in acute deep-vein thrombosis and pulmonary embolism; Risks associated with the use of thrombolytic...

  • Expanding thrombolysis to older adults, others could triple lives saved.  // Geriatrics;Mar1993, Vol. 48 Issue 3, p22 

    The article reports on the expansion of the U.S. guidelines for thrombolytic therapy. Thrombolytic therapy for acute MI saves 7,200 U.S. lives per year and expanding its use to patients with a favorable risk-benefit ratio could triple the number of lives saved. The current eligibility criteria...

  • THE TREATMENT OF PULMONARY EMBOLISM WITH FIBRINOLYSIN. Sheffer, Albert L.; Israel, Harold L. // Angiology;Aug1959 Part 2, Vol. 10 Issue 4, p292 

    An attempt has been made to evaluate fibrinolysin in 33 patients treated for pulmonary embolism or related thrombolic diseases. Six cases of pulmonary embolism are presented in detail. The results suggest that fibrinolysin by itself may not be effective in preventing recurrent embolism. However,...

  • Acute improvement in right ventricular function after treatment of presumed massive pulmonary embolism with thrombolytics. Brittain, Evan L.; Janz, David R.; Monahan, Kenneth J.; Sevin, Carla M. // Pulmonary Circulation;Oct-Dec2012, Vol. 2 Issue 4, p522 

    Acute massive pulmonary embolism results in a rise in pulmonary vascular resistance and acute right ventricular dilation and systolic dysfunction. In unstable patients who cannot safely undergo computed tomography, echocardiography can often provide direct and indirect evidence of pulmonary...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics