TITLE

Benign and Malignant Disease Caused by EBV

AUTHOR(S)
Wolf, Hans; Seibl, Rudolf
PUB. DATE
July 1984
SOURCE
Journal of Investigative Dermatology;Jul84 Supplement, Vol. 83, p88s
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Epstein-Barr virus (EBV) causes infectious mononucleosis as a primary disease. The virus infects more than 90% of the average population and persists lifelong in peripheral B-lymphocytes. The virus is produced in the parotid gland and spread via the oral route. Serology suggests that the Epstein-Barr virus might be involved in the causation of two neoplastic diseases of humans: African Burkitt's lymphoma and nasopharyngeal carcinoma. Whereas the development of the lymphoma has an even better linkage with chromosomal rearrangements, nasopharyngeal carcinoma shows a unique association with Epstein-Barr virus. Environmental factors, including traditional Chinese medicine, may be responsible for the enhanced risk of nasopharyngeal carcinoma in certain, predominantly Chinese, populations of southern Asia. Possible mechanisms leading to the establishment of the neoplastic manifestations will be discussed.
ACCESSION #
12281504

 

Related Articles

  • Bilateral Facial Palsy. Weintraub, Michael I. // Clinical Pediatrics;Dec1977, Vol. 16 Issue 12, p1158 

    The article focuses on a case study related to infectious mononucleosis, a common systemic illness primarily involving children and young adults and due apparently to the Epstein-Barr virus. A 15-year-old-girl developed sore throat, cervical adenopathy, and swallowing difficulty. She received...

  • Infectious Mononucleosis in Active Patients. Auwaerter, Paul G. // Physician & Sportsmedicine;Nov2002, Vol. 30 Issue 11, p43 

    IN BRIEF: Infectious mononucleosis may account for considerable illness, especially among adolescents and young adults. Although the disorder was well described more than 70 years ago as involving fever, sore throat, and lymphadenopathy, questions often arise about diagnosis and management....

  • Epstein-Barr virus rarely causes neurologic disease. Dale, David C.; Federman, Daniel D. // Cortlandt Forum;09/25/97, Vol. 10 Issue 9, p28 

    Reports that Epstein-Barr virus (EBV) causes infectious mononucleosis and has been implicated as a cause of nasopharyngeal carcinoma and Burkitt's lymphoma. Primary infection of humans; Presence in adults of antibody to EBV; Diseases that can result from the virus.

  • Hemolytic uremic syndrome linked to infectious mononucleosis. Simonetti, Giacomo D.; Dumont-Dos Santos, Kristina; Pachlopnik, Jana M.; Ramelli, Gianpaolo; Bianchetti, Mario G. // Pediatric Nephrology;Nov2003, Vol. 18 Issue 11, p1193 

    Abstract A 12-month-old boy developed a mild hemolytic uremic syndrome with no acute diarrheal prodrome. The typical clinical, hematological, and serological features of infectious mononucleosis were also noted. The clinical course of both hemolytic uremic syndrome and infectious mononucleosis...

  • Primary Epstein-Barr virus infection with polyradiculitis: a case report. Hottenrott, Tilmann; Rauer, Sebastian; Bäuerle, Jochen // BMC Neurology;2013, Vol. 13 Issue 1, p1 

    Background: Nervous system complications of primary Epstein-Barr virus (EBV) infection in adults are rare, but may occur with encephalitis, meningitis, myelitis, cranial and peripheral neuropathies, or radiculitis. Case presentation: We describe an immune competent adult with a primary EBV...

  • Postinfectious Glomerulonephritis and Epstein-Barr Virus Co-Infection.  // Collegium Antropologicum;Apr2010 Supplement 2, Vol. 34 Issue 2, p229 

    No abstract available.

  • Epstein–Barr virus-associated infectious mononucleosis and risk of systemic lupus erythematosus. Ulff-Møller, Constance J.; Nielsen, Nete M.; Rostgaard, Klaus; Hjalgrim, Henrik; Frisch, Morten // Rheumatology;Sep2010, Vol. 49 Issue 9, p1706 

    Objectives. Elevated levels of serological markers of EBV infection in patients with SLE and observations that infectious mononucleosis (IM) may precede some cases of SLE suggest a possible role of EBV in the aetiology of SLE. We evaluated the relationship between EBV-associated IM and...

  • A Case of Severe Chronic Active Infection with Epstein-Barr Virus: Immunologic Deficiencies Associated with a Lytic Virus Strain. Schwarzmann, Fritz; von Baehr, Rüdiger; Jäger, Michael; Prang, Nadja; Böhm, Stephan; Reischl, Udo; Wolf, Hans; Bieger, W.P. // Clinical Infectious Diseases;9/1/1999, Vol. 29 Issue 3, p626 

    Reports on a case of a woman who acquired infectious mononucleosis at the age of 15 years and then suffered for more than 12 years until she died of liver failure. Background information on the Epstein-Barr virus (EBV), primary cause of infectious mononucleosis; Rare strains of EBV; Details on...

  • Infectious mononucleosis screening in quinsy patients. Ahmad, Umear A.; Anari, Shahram // European Archives of Oto-Rhino-Laryngology;Jan2010, Vol. 267 Issue 1, p113 

    There have been conflicting recommendations in the literature with regards to the screening of infectious mononucleosis (IM) in quinsy patients. Our aim was to ascertain an accurate rate of IM in quinsy patients and find any criterion by which we can decide which quinsy patient to screen for IM....

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics