Pneumocystis carinii Pneumonia in a 3-Month-Old Infant Receiving High-Dose Corticosteroid Therapy for Airway Hemangiomas

Aviles, Roger; Boyce, Thomas G.; Thompson, Dana M.
February 2004
Mayo Clinic Proceedings;Feb2004, Vol. 79 Issue 2, p243
Academic Journal
Primary infection with Pneumocystis carinii usually occurs early in life, and young infants receiving prolonged treatment with high-dose corticosteroids may be at risk for the development of symptomatic disease. Prophylaxis with trimethoprim-sulfamethoxazole is safe and effective and should be considered for such infants, particularly those with underlying airway abnormalities. We describe a 3-month-old immunocompetent infant who developed severe P carinii pneumonia after 6 weeks of high-dose corticosteroid therapy for cervicofacial and airway hemangiomas. AIDS = acquired immunodeficiency syndrome; PCP = Pneumocystis carinii pneumonia.


Related Articles

  • PCP prophylaxis with use of corticosteroids by neurologists. Kelly, Dearbhla M.; Cronin, Simon // Practical Neurology (BMJ Publishing Group);Apr2014, Vol. 14 Issue 2, p74 

    Pneumocystis jirovecii pneumonia (PCP) is increasingly reported in patients without HIV. Corticosteroids are a major risk factor, with up to 90% of patients receiving corticosteroid treatment prior to the development of PCP. In view of this, many specialties now prescribe PCP prophylaxis to...

  • Corticosteroids as Adjunctive Therapy for Severe Pneumocystis carinii Pneumonia in Non-Human Immunodeficiency Virus-Infected Patients: Retrospective Study of 31 Patients. Delclaux, Christophe; Zahar, Jean-Ralph; Amraoui, Gibba; Leleu, Ghislaine; Lebargy, Fran├žois; Brochard, Laurent; Schlemmer, Benoit; Brun-Buisson, Christian // Clinical Infectious Diseases;9/1/1999, Vol. 29 Issue 3, p670 

    Presents a study that assessed whether corticosteroid adjunctive therapy (CAT) could prevent death in patients with Pneumocystis carinii pneumonia (PCP) but not HIV-infected. Background information on PCP; Purpose of corticosteroids; Effect of CAT on patients with PCP.

  • Corticosteroids Prevent Early Deterioration in Patients with Moderately Severe Pneumocystis carinii Pneumonia and the Acquired Immundeficiency Syndrome (AIDS). Montaner, Julio S.G.; Lawson, Lindsay M.; Levitt, Nirvair; Belzberg, Allan; Schechter, Martin T.; Ruedy, John // Annals of Internal Medicine;7/1/90, Vol. 113 Issue 1, p14 

    Determines whether oral corticosteroids can prevent early deterioration in patients with AIDS-related Pneumocystis carinii pneumonia. Application of sequential analysis; Overview of intention-to-treat analysis; Median oxygen saturation at rest, median lactic dehydrogenase and median exercise...

  • Pneumocystis Carinii pneumonia complicating corticosteroid therapy in acute severe alcoholic hepatitis. Gautam, Manjushree; Rattan, Sushil; Ajit, Chala; Rothstein, Kenneth // American Journal of Gastroenterology;Sep2003 Supplement, Vol. 98, pS99 

    An abstract of the article " Pneumocystis Carinii Pneumonia Complicating Corticosteroid Therapy in Acute Severe Alcoholic Hepatitis," by Manjushree Gautam, Sushil Rattan, Chala Ajit and Kenneth Rothstein is presented.

  • Inappropriate use of steroid and Pneumocystis jiroveci pneumonia: report of two cases. Tabarsi, P.; Mirsaeidi, M.; Amiri, M.; Karimi, S.; Masjedi, M. R.; Mansouri, D. // Eastern Mediterranean Health Journal;sep/oct2008, Vol. 14 Issue 5, p1217 

    The article describes two cases of pneumocystis pneumonia (PCP) that resulted from the incorrect use of corticosteroids. The presence of diffuse oral candidiasis, lymphocytopenia and ground glass lesions in high resolution lung computed tomography (CT) scans guided the physicians to the correct...

  • Are Corticosteroids Beneficial as Adjunctive Therapy for Pneumocystis Pneumonia in AIDS? Kovacs, Joseph A.; Masur, Henry // Annals of Internal Medicine;7/1/90, Vol. 113 Issue 1, p1 

    Editorial. Deals with treating pneumocystis pneumonia associated with AIDS. Occurrence of progressive desaturation after initiation of therapy; Use of corticosteroids as adjuvants to specific antipneumocystis therapy; Results of a placebo-controlled trial that assessed the effects of...

  • Pneumocystis carinii Pneumonia in Patients with Ulcerative Colitis Treated with Corticosteroids. Bernstein, Charles N.; Kolodny, Marvin; Block, Edward; Shanahan, Fergus // American Journal of Gastroenterology;Apr1993, Vol. 88 Issue 4, p574 

    Today, Pneumocystis carinii pneumonia (PCP) is typically associated with AIDS. However, in the pre-AIDS era, PCP was known to he associated with various immunodeficiency states, malignancies, and immunosuppressive therapy, particularly the use of corticosteroids. PCP has been reported to occur...

  • A 21-Day of Adjunctive Corticosteroid Use May Not Be Necessary for HIV-1-Infected Pneumocystis Pneumonia with Moderate and Severe Disease. Shibata, Satoshi; Nishijima, Takeshi; Aoki, Takahiro; Tanabe, Yoshinari; Teruya, Katsuji; Kikuchi, Yoshimi; Kikuchi, Toshiaki; Oka, Shinichi; Gatanaga, Hiroyuki // PLoS ONE;9/22/2015, Vol. 10 Issue 9, p1 

    Background: The current guidelines recommend 21-day adjunctive corticosteroid therapy for HIV-1-infected pneumocystis pneumonia patients (HIV-PCP) with moderate-to-severe disease. Whether shorter adjunctive corticosteroid therapy is feasible in such patients is unknown. Methods: We conducted a...

  • pneumocystis pneumonia. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p615 

    An encyclopedia entry for "pneumocystis pneumonia" is presented. It refers to a lung infection caused by pneumocystis carinii. It is an opportunistic infection that is dangerous to people with impaired resistance to infection. Some of its symptoms are fever, dry cough and shortness of breath....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics