Intravenous N-acetylcysteine prevented contrast nephropathy: COMMENTARY

Barrett, Brendan
January 2004
ACP Journal Club;Jan/Feb2004, Vol. 140 Issue 1, p16
Academic Journal
This article focuses on a study regarding a rapid protocol for the prevention of contrast-induced renal dysfunction, published in the 2003 issue of "Journal of the American College of Cardiology." Prevention of contrast nephropathy is important for patients who are at risk because the consequences may include dialysis or death. The rapid IV N-acetyl-cysteine (NAC) protocol used in the study showed efficacy similar to other clinical trials using more prolonged, lower-dose oral regimens. The results from this study support the growing body of evidence favoring the use of NAC and extend our knowledge of its dosage and route of administration.


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