TITLE

Review: Anticholinergic drugs improve motor function and disability in Parkinson disease: COMMENTARY

AUTHOR(S)
Holloway, Robert; Frank, Sam
PUB. DATE
January 2004
SOURCE
ACP Journal Club;Jan/Feb2004, Vol. 140 Issue 1, p15
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on a study regarding anticholinergics for symptomatic management of parkinson's disease (PD), published in the 2003 issue of the journal "Cochrane Database of Systematic Reviews." In the authors' opinion, the study reminds us that most of what we do in medicine is based on nonrandomized studies and clinical experience. The authors say that clinical trials included in the study are old, heterogeneous, and of such poor quality that only limited conclusions can be drawn. Most patients with PD can be managed without anticholinergics, but if one chooses to use them, they should be used primarily to treat troubling parkinsonian tremor, either as initial treatment or if tremor continues to be bothersome despite dopaminergic therapy.
ACCESSION #
12104551

 

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