Review: Omalizumab reduces asthma exacerbations and daily steroid use: COMMENTARY

Thien, Frank
January 2004
ACP Journal Club;Jan/Feb2004, Vol. 140 Issue 1, p13
Academic Journal
This article focuses on a study regarding anti-immunoglobulin E for chronic asthma, published in the 2003 issue of the journal "Cochrane Database of Systematic Reviews." The role of monoclonal anti-immunoglobulin E antibodies in clinical asthma management continues to evolve. The meta-analysis confirms the clinical benefits of anti-immunoglobulin E therapy, including the reduction of asthma exacerbations and decreasing the requirement for preventive inhaled steroids. Furthermore, this benefit is evident in a range of asthma severity, including severe asthma where immunoglobulin E was thought to be less important. The cost of the medication is about U.S. $10,000 per year, which far exceeds other forms of asthma treatment.


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