TITLE

Ticlopidine was not better than aspirin for preventing recurrent stroke in African-Americans with noncadioembolic ischemic stroke: COMMENTARY

AUTHOR(S)
Johnston, S. Claiborne
PUB. DATE
January 2004
SOURCE
ACP Journal Club;Jan/Feb2004, Vol. 140 Issue 1, p9
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on a study regarding aspirin and ticlopidine for prevention of recurrent stroke in Afro-American patients, published in the 2003 issue of "Journal of the American Medical Association." In the author's opinion, in studies of stroke prevention, results for whites may not be directly generalizable to Afro-Americans. The burden of stroke is greater among Afro-Americans than whites, and this may be explained by an uneven distribution of known risk factors, disparities in how well these risk factors are treated, genetic and other unidentified risk factors, or the distribution of stroke subtypes. Clopidogrel has largely replaced ticlopidine as the nonaspirin antiplatelet agent of choice for the prevention of stroke and cardiovascular events because it is associated with fewer major adverse events.
ACCESSION #
12104539

 

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