Simvastatin reduced mortality and vascular events in diabetes mellitus

January 2004
ACP Journal Club;Jan/Feb2004, Vol. 140 Issue 1, p1
Academic Journal
This article focuses on a study related to patients with diabetes mellitus, published in the 2003 issue of the journal "Lancet." It is a heart protection study of cholesterol-lowering with simvastatin drug in 5963 people with diabetes. The patients had a medical history of diabetes mellitus, coronary heart disease, occlusive disease of noncoronary arteries, or treated hypertension. After a run-in phase, compliant patients were allocated to simvastatin. Patients in each group were also allocated to antioxidants or placebo. Patients in the simvastatin group had fewer coronary events, strokes, revascularization procedures, and major vascular events.


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