TITLE

Severe West Nile Virus Disease in Healthy Adults

AUTHOR(S)
Emig, Mimi; Apple, Douglas J.
PUB. DATE
January 2004
SOURCE
Clinical Infectious Diseases;1/15/2004, Vol. 38 Issue 2, p289
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The inpatient records of 44 case patients with West Nile virus infection hospitalized in 2002 were reviewed. Sixty-five percent of the case patients had encephalitis, and 35% had aseptic meningitis. There was no significant difference in the distribution of aseptic meningitis versus encephalitis among adults aged ≤50 years compared with adults aged ≥65 years. Focal weakness, likely due to anterior horn cell involvement, was present in 10 case patients (overall rate, 23%; rate among patients with encephalitis, 34%). Case patients with focal weakness who were aged ≤50 years had monoparesis, whereas those aged ≥65 years had paraparesis or quadriparesis. The overall mortality rate was 14%, and the mortality rate in patients aged ≥65 years was 35%. Increased age was associated with an increased mortality rate. The presence of paraparesis or quadriparesis was not independently predictive of mortality.
ACCESSION #
12082292

 

Related Articles

  • Inhibition of apoptosis prevents West Nile virus induced cell death. Kleinschmidt, Malte C.; Michaelis, Martin; Ogbomo, Henry; Doerr, Hans-Wilhelm; Cinatl Jr, Jindrich // BMC Microbiology;2007, Vol. 7, p49 

    Background: West Nile virus (WNV) infection can cause severe meningitis and encephalitis in humans. Apoptosis was recently shown to contribute to the pathogenesis of WNV encephalitis. Here, we used WNV-infected glioma cells to study WNV-replication and WNV-induced apoptosis in human...

  • West Nile virus warning.  // GP: General Practitioner;11/18/2002, p19 

    Reports that general practitioners have been warned to consider West Nile virus as the cause of encephalitis or viral meningitis if patients have travelled to North America. Concerns over the outbreak of the disease in the U.S. and Canada; Places where the outbreak have occurred; Incubation...

  • Protective Behavior and West Nile Virus Risk. Loeb, Mark; Elliott, Susan J.; Gibson, Brian; Fearon, Margaret; Nosal, Robert; Drebot, Michael; D'Cuhna, Colin; Harrington, Daniel; Smith, Stephanie; George, Pauline; Eyles, John // Emerging Infectious Diseases;Sep2005, Vol. 11 Issue 9, p1433 

    We conducted a cross-sectional, household survey in Oakville, Ontario, where an outbreak of West Nile virus (WNV) in 2002 led to an unprecedented number of cases of meningitis and encephalitis. Practicing ≥2 personal protective behavior traits reduced the risk for WNV infection by half.

  • Lineage 1 and 2 Strains of Encephalitic West Nile Virus, Central Europe. Bakonyi, Tamás; Ivanics, Éva; Erdélyi, Károly; Ursu, Krisztina; Ferenczi, Emöke; Weissenböck, Herbert; Nowotny, Norbert // Emerging Infectious Diseases;Apr2006, Vol. 12 Issue 4, p618 

    Two different West Nile virus (WNV) strains caused lethal encephalitis in a flock of geese and a goshawk in southeastern Hungary in 2003 and 2004, respectively. During the outbreak in geese, 14 confirmed human cases of WNV encephalitis and meningitis were reported in the same area. Sequencing of...

  • Use of Interferon-α in Patients with West Nile Encephalitis: Report of 2 Cases. Kalil, Andre C.; Devetten, Marcel P.; Singh, Sanjay; Lesiak, Brandi; Poage, David P.; Bargenquast, Kim; Fayad, Pierre; Freifeld, Alison G. // Clinical Infectious Diseases;3/1/2005, Vol. 40 Issue 5, p764 

    We describe 2 patients with West Nile virus (WNV) encephalitis who were treated experimentally with interferon (IFN)- α. Both patients demonstrated substantial improvement in mentation and speech on the second day of experimental therapy, and neither required endotracheal intubation or...

  • West Nile Virus Activity Update. Chatfield, Joanne E. // American Family Physician;12/15/2001, Vol. 64 Issue 12, p2019 

    Focuses on a report published by the Centers for Disease Control and Prevention in the July 27, 2001 issue of "Morbidity and Mortality Weekly Report," which details virus activity in the United States. Spread of the West Nile virus in the U.S.; Need for control and preventive measures; How the...

  • Enterovirus infection, not WNV. Kemper, Carol A. // Infectious Disease Alert;Apr2008, Vol. 27 Issue 7, p84 

    The article reports on the results of an examination conducted by the Los Angeles County Public Health Department Laboratory in California on Cerebrospinal Fluid (CSF) specimen submitted for West Nile Virus (WNV) testing for the presence of enterovirus. Accordingly, all of the patients were...

  • Delayed-onset and recurrent limb weakness associated with West Nile virus infection. Sejvar, James J.; Davis, Larry E.; Szabados, Erica; Jackson, Alan C. // Journal of NeuroVirology;Feb2010, Vol. 16 Issue 1, p93 

    Human neurologic illness following infection with West Nile virus (WNV) may include meningitis, encephalitis, and acute flaccid paralysis (AFP). Most WNV-associated AFP is due to involvement of the spinal motor neurons producing an anterior (polio)myelitis. WNV poliomyelitis is typically...

  • WEST NILE VIRUS. Steiger, Brad; Steiger, Sherry // Conspiracies & Secret Societies;2006, p493 

    An encyclopedia entry for "West Nile Virus (WNV)" is presented. It refers to the virus responsible for encephalitis and meningitis. This virus was first identified by virologists in 1937 in the West Nile district of Uganda. According to the belief of some conspiracy theorists, Cuban President...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics