Nutritionally Variant Streptococcal Infections at a University Hospital in Taiwan: Disease Emergence and High Prevalence of Î’ -Lactam and Macrolide Resistance

Chung-Hsin Liao, John J.; Lee-Jene Teng; Po-Ren Hsueh; Yu-Chi Chen; Li-Min Huang; Shan-Chwen Chang; Shen-Wu Ho
February 2004
Clinical Infectious Diseases;2/1/2004, Vol. 38 Issue 3, p452
Academic Journal
From January 1993 to December 2002, 28 patients with nutritionally variant streptococci (NVS) infections were treated at a university hospital in Taiwan. Twelve (43%) of these patients had various underlying malignancies, and 7 (25%) had underlying valvular heart diseases. Nine patients (32%) had infective endocarditis, and 9 (32%) had primary bacteremia. The deaths of 7 patients (25%) were directly related to NVS infection. Among the 28 isolates recovered from these patients, 50% were not susceptible to penicillin, 33% were not susceptible to cefotaxime, and 93% were not susceptible to azithromycin.


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