TITLE

Analyzing Sleep Abnormalities in HIV-Infected Patients Treated with Efavirenz

AUTHOR(S)
Gallego, Lucía; Barreiro, Pablo; del Río, Rafael; de Requena, Daniel González; Rodríguez-Albari&nteldi;o, Apolinar; Gonzá-Lahoz, Juan; Soriano, Vincent
PUB. DATE
February 2004
SOURCE
Clinical Infectious Diseases;2/1/2004, Vol. 38 Issue 3, p430
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Ambulatory electroencephalogram monitoring was performed for 18 HIV-infected subjects treated with efavirenz with and without insomnia and for 13 healthy control subjects. All patients receiving efavirenz had longer sleep latencies and shorter duration of deep sleep, although poor sleepers also showed reduced sleep efficiency and shorter duration of rapid eye movement sleep. Efavirenz plasma levels were higher in patients with insomnia and/or reduced sleep efficiency.
ACCESSION #
12080524

 

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