Multidrug-Resistant Escherichia coli Clonal Groups Causing Community-Acquired Pyelonephritis

Manges, Amee R.; Dietrich, Peter S.; Tiley, Lee W.
February 2004
Clinical Infectious Diseases;2/1/2004, Vol. 38 Issue 3, p329
Academic Journal
From October 1999 through January 2000, an Escherichia coli clonal group (designated ‘CgA’) was isolated from the urine of nearly one-half of all women with urinary tract infections (UTIs) caused by trimethoprim-sulfamethoxazole (TMP-SMZ)–­resistant E. coli in a California community. This study describes the prevalence of pyelonephritis caused by CgA in the same community. E. coli isolates were characterized by enterobacterial repetitive intergenic consensus (ERIC2) polymerase chain reaction (PCR), serogrouping, and pulsed-field gel electrophoresis. Fourteen (11%) of 130 women with UTIs received a diagnosis of pyelonephritis. CgA was associated with 4 (57%) of the 7 pyelonephritis cases caused by TMP-SMZ­resistant E. coli and was associated with none of the cases caused by TMP-SMZ­susceptible E. coli (P<.02). Six (86%) of these TMP-SMZ­resistant E. coli isolates belonged to 2 distinct ERIC2 PCR­defined clonal groups, whereas all of the TMP-SMZ­susceptible E. coli strains had unique fingerprints (P<.001). The prevalence of antimicrobial­resistant pyelonephritis in a community may be affected by a limited number of E. coli clonal groups.


Related Articles

  • Effect of iron on acute pyelonephritis and later chronic changes. Guze, Lucien B.; Guze, Phyllis A.; Kalmanson, George M.; Glassock, Richard J. // Kidney International;Jun1982, Vol. 21 Issue 6, p808 

    Administration of iron to rats exacerbated early inflammatory changes of pyelonephritis produced by intravenous inoculation of Escherichia coli. This effect was noted with four of eight strains of E. coli tested and was dependent on bacterial inoculum. Despite this increase in severity of acute...

  • Binding to and killing of human renal epithelial cells by hemolytic P-fimbriated E. coli. Trifillis,, Anna L.; Donnenberg, Michael S.; Cui, Xiaoling; Russell, Robert G.; Utsalo, Simon J.; Mobley, Harry L. T.; Warren, John W. // Kidney International;Oct1994, Vol. 46 Issue 4, p1083 

    Acute pyelonephritis is a common invasive infection frequently caused by E. coli that possess P-fimbriae and secrete hemolysin. We have examined the role of P fimbriae and hemolysin in the killing of putative target cells of acute pyelonephritis, that is, human renal epithelial cells (HRPTEC)....

  • Norfloxacin.  // Reactions Weekly;5/25/2013, Issue 1454, p32 

    An abstract of the article "Community acquired quinolone-resistant escherichia coli pyelonephritis complicated with multiple renal abscesses: A case report," by M. Katsiari and colleagues is presented.

  • Escherichia coli 0157 enterohaemorrhagic colitis associated with pyelonephritis: CT findings. Heffernan, E.; Chatur, N.; Zwirewich, C. // British Journal of Radiology;Apr2009, Vol. 82 Issue 976, pe63 

    Escherichia coli 0157:H7 is increasingly being recognized as a cause of infectious colitis, which typically results in bloody diarrhoea in an afebrile patient. The absence of fever often means that an infectious process is not considered in the differential diagnosis, particularly as this...

  • Virulence of wild-type E. coli uroisolates in experimental pyelonephritis. Domingue, Gerald J.; Laucirica, Rodolfo; Baliga, Prabhakar; Covington, Steve; Robledo, Jaime A.; Su-Chen Li // Kidney International;Dec1988, Vol. 34 Issue 6, p761 

    This study was designed to analyze the colonizing and invasive properties of wild-type bacteriuric E. coli possessing a variety of phenotypic characteristics in experimental nonobstructive pyelonephritis (P and Type 1 [T] fimbriae, hemolysin [Hly], presence of K capsules, flagella [H], serotype,...

  • Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis. Roelofs, Joris J. T. H.; Teske, Gwendoline J. D.; Bonta, Peter I.; de Vries, Carlie J. M.; Meijers, Joost C. M.; Weening, Jan J.; van der Poll, Tom; Florquin, Sandrine // Kidney International;Jan2009, Vol. 75 Issue 1, p52 

    Acute pyelonephritis, frequently caused by Escherichia coli, is a substantial health problem. Plasminogen activator inhibitor type-1 (PAI-1) not only inhibits plasminogen activation but is also involved in cell migration. To determine if it has a role in host defense, we induced pyelonephritis...

  • Emphysematous pyelonephritis in a diabetic patient with autosomal dominant polycystic kidney disease. Hong Seok Lee; Ji Hye Jang; Yeong bok Lee; Young Ok Kim // British Journal of Hospital Medicine (17508460);Apr2014, Vol. 75 Issue 4, p235 

    The article describes the case of a 77-year-old woman who presented with fever and left flank pain. Cystic infection with abscess was revealed by computed tomography, as well as emphysematous pyelonephritis along with cystic infection revealing wall thickening. The patient was treated with...

  • Pyelonephritis in slaughter pigs and sows: Morphological characterization and aspects of pathogenesis and aetiology. Isling, Louise K.; Aalbæk, Bent; Schrølder, Malene; Leifsson, Páll S. // Acta Veterinaria Scandinavica;2010, Vol. 52, p48 

    Background: Pyelonephritis is a serious disease in pig production that needs to be further studied. The purpose of this study was to describe the morphology, investigate the pathogenesis, and evaluate the aetiological role of Escherichia coli in pyelonephritis in slaughtered pigs by concurrent...

  • Emphysematous cyst infection in autosomal dominant polycystic kidney disease. Yamanouchi, Masayuki; Ubara, Yoshifumi; Takaichi, Kenmei // Clinical & Experimental Nephrology;Jun2012, Vol. 16 Issue 3, p505 

    No abstract available.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics