Surveillance for transmission of lymphatic filariasis in Colombo and Gampaha districts of Sri Lanka following mass drug administration

Chandrasena, Nilmini T. G. A.; Premaratna, Ranjan; Samarasekera, Dilhani S.; de Silva, Nilanthi R.
October 2016
Transactions of the Royal Society of Tropical Medicine & Hygiene;Oct2016, Vol. 110 Issue 10, p620
Academic Journal
Background: Sri Lanka was recently declared by WHO to have eliminated lymphatic filariasis as a public health problem, after conclusion of annual mass drug administration. Our aim was to assess the lymphatic filariasis situation, following mass drug administration. Methods: Surveillance was done in two districts of the Western Province in two consecutive phases (2009-2010 and 2013-2015), by examining 2461 thick night blood smears and performing 250 dipstick tests on children for antibodies to Brugia malayi. Results and Conclusions: Decline in bancroftian microfilaraemia (microfilaria rate 0.32% to zero) supports elimination, but re-emergence of brugian filariasisis (antibody rate, 1.6%; one microfilaria positive) is a cause for concern.


Related Articles

  • Assessing Coverage and Compliance of Mass Drug Administration Under Elimination of Lymphatic Filariasis Program in Yadgir District, Karnataka. Shetty, Achal; Santhuram, Anil Navale; S. J., Nareshkumar // International Journal of Medical Science & Public Health;2012, Vol. 1 Issue 2, p71 

    Background: Evaluation of mass drug administration (MDA) is done internally by the health authorities and externally by independent agencies. This paper reports the findings of evaluation of MDA conducted independently for Government of India in Yadgir district of Karnataka state in February...

  • Helminth infection in coldwater fishes of Suru river Ladakh, Jammu and Kashmir, India. Ahmad Dar, Shabir; Ahmed, Fayaz; Mir, M. R.; Dar, J. A.; Tak, Hidayatullah; Kuchai, J. A. // Recent Research in Science & Technology;Dec2012, Vol. 4 Issue 12, p1 

    A helminthological survey of coldwater fishes of Ladakh was carried out from November 2007 to April 2009 (18 months). A total of 93 fishes belonging to two species viz., Schizothorax plagiostomus and Diptychus maculatus were collected and examined from different collection sites of Suru river,...

  • Albendazole Induced Rupture Of Pulmonary Hydatid Cysts. Fallatah, Hind I.; Akbar, Hisham O. // Internet Journal of Gastroenterology;2010, Vol. 9 Issue 2, p9 

    Massive gastrointestinal bleeding from the small intestine un common, It is usually a complication advanced local small bowel pathology or vascular abnormalities. Parasitc infections causing gastrointestinal bleeding is usually a feature of large bowel prasitc infestations. Small parasitic...

  • Diethylcarbamazine Increases Activation of Voltage-Activated Potassium (SLO-1) Currents in Ascaris suum and Potentiates Effects of Emodepside. Buxton, Samuel K.; Robertson, Alan P.; Martin, Richard J. // PLoS Neglected Tropical Diseases;Nov2014, Vol. 8 Issue 11, p1 

    Diethylcarbamazine is a drug that is used for the treatment of filariasis in humans and animals; it also has effects on intestinal nematodes, but its mechanism of action remains unclear. Emodepside is a resistance-busting anthelmintic approved for treating intestinal parasitic nematodes in...

  • Exploring the Potential of Flubendazole in Filariasis Control: Evaluation of the Systemic Exposure for Different Pharmaceutical Preparations. Ceballos, Laura; Mackenzie, Charles; Geary, Timothy; Alvarez, Luis; Lanusse, Carlos // PLoS Neglected Tropical Diseases;May2014, Vol. 8 Issue 5, p1 

    The goal of elimination of the human filariases would benefit greatly from the use of a macrofilaricidal agent. In vivo trials in humans and many experimental animal models suggest that flubendazole (FLBZ) is a highly efficacious macrofilaricide. However, since serious injection site reactions...

  • Change in composition of the Anopheles gambiae complex and its possible implications for the transmission of malaria and lymphatic filariasis in north-eastern Tanzania. Derua, Yahya A; Alifrangis, Michael; Hosea, Kenneth M; Meyrowitsch, Dan W; Magesa, Stephen M; Pedersen, Erling M; Simonsen, Paul E // Malaria Journal;2012, Vol. 11 Issue 1, p188 

    Background: A dramatic decline in the incidence of malaria due to Plasmodium falciparum infection in coastal East Africa has recently been reported to be paralleled (or even preceded) by an equally dramatic decline in malaria vector density, despite absence of organized vector control. As part...

  • Epidemiological assessment of neglected diseases in children: lymphatic filariasis and soil-transmitted helminthiasis. Aguiar-Santos, Ana M.; Medeiros, Zulma; Bonfim, Cristine; Rocha, Abraham C.; Brandào, Eduardo; Miranda, Tereza; Oliviera, Paula; Sarinho, Emanuel S. C. // Jornal de Pediatria;May/Jun2013, Vol. 89 Issue 3, p250 

    Objective: To report the prevalence of lymphatic filariasis and intestinal parasitic infections in school-aged children living in a filariasis endemic area and discuss about the therapeutic regimen adopted in Brazil for the large-scale treatment of filariasis. Methods: A cross-sectional study...

  • Filariasis In The Arm--A Diagnostic Enigma! Correia, Mervyn; Amonkar, Dilip; Audi, Pandarinath; Bhat, Chaitra; Cruz, Peter; Mitta, Nivedita; Pednekar, Amey; Kurane, Prakash // Internet Journal of Surgery;2010, Vol. 25 Issue 2, p1 

    Lymphatic filariasis is a disease of the tropics. It is caused by infection with any of several round, thread-like parasitic worms. This most commonly occurs due to infection with a parasite that lives in the lymph system. This is called lymphatic filariasis. The parasite is spread from person...

  • DISTRIBUIÇÃO DE LARVAS DE NEMATÓDEOS GASTRINTESTINAIS DE OVINOS EM PASTAGENS DE INVERNO. Gazda, Tatiana Louise; Piazzetta, Ricardo Guimarães; Dittrich, João Ricardo; Monteiro, Alda Lúcia Gomes; Soccol, Vanete Thomaz // Ciência Animal Brasileira;2012, Vol. 13 Issue 1, p85 

    The aim of this work was to study the dynamics of nematode larvae of sheep on winter pasture species. A completely randomized design was used. The treatments were composed by two different dry matter offers of each forage species (black oat 5% and 12%; ryegrass 10% and 20%). A total of 28...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics