TITLE

Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration

AUTHOR(S)
Lopez, Gerardo A.; Estevez, M.-Carmen; Soler, Maria; Lechuga, Laura M.
PUB. DATE
January 2017
SOURCE
Nanophotonics (21928606);Jan2017, Vol. 6 Issue 1, p123
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Motivated by the recent progress in the nanofabrication field and the increasing demand for cost-effective, portable, and easy-to-use point-of-care platforms, localized surface plasmon resonance (LSPR) biosensors have been subjected to a great scientific interest in the last few years. The progress observed in the research of this nanoplasmonic technology is remarkable not only from a nanostructure fabrication point of view but also in the complete development and integration of operative devices and their application. The potential benefits that LSPR biosensors can offer, such as sensor miniaturization, multiplexing opportunities, and enhanced performances, have quickly positioned them as an interesting candidate in the design of lab-on-a-chip (LOC) optical biosensor platforms. This review covers specifically the most significant achievements that occurred in recent years towards the integration of this technology in compact devices, with views of obtaining LOC devices. We also discuss the most relevant examples of the use of the nanoplasmonic biosensors for real bioanalytical and clinical applications from assay development and validation to the identification of the implications, requirements, and challenges to be surpassed to achieve fully operative devices.
ACCESSION #
119944047

 

Related Articles

  • A chip-based assay for botulinum neurotoxin A activity in pharmaceutical preparations. Lévêque, Christian; Ferracci, Géraldine; Maulet, Yves; Grand-Masson, Chloé; Seagar, Michael; Far, Oussama // Applied Microbiology & Biotechnology;May2015, Vol. 99 Issue 10, p4355 

    The production of botulinum neurotoxin A (BoNT/A) for therapeutic and cosmetic applications requires precise determination of batch potency, and the enzymatic activity of BoNT/A light chain is a crucial index that can be measured in vitro. We previously established a SNAP-25 chip-based assay...

  • No job too small.  // Nature Materials;Jun2008, Vol. 7 Issue 6, p419 

    The article discusses various reports published within the issue including one on surface plasmon effects and another on successful imaging approach by surface plasmon.

  • Determination of Binding Potency of Peptidic Inhibitors of Grb2-SH2 by Using the Protein-Captured Biosensor Method. Lung, Feng-Di T.; Wan-Ching Li; Yung-Hsien Chang; Hui-Ming Chen // Protein & Peptide Letters;Aug2008, Vol. 15 Issue 8, p806 

    The growth factor receptor-binding protein 2-Src homology 2 (Grb2-SH2) domain plays an important role in the oncogenic Ras signal transduction pathway, therefore, peptidic inhibitors of the Grb2-SH2 domain has been chosen as our target for the development of antiproliferative agents. The...

  • Plasmonic Sensors Based on Doubly-Deposited Tapered Optical Fibers. González-Cano, Agustín; Navarrete, María-Cruz; Esteban, Óscar; Díaz-Herrera, Natalia // Sensors (14248220);Mar2014, Vol. 14 Issue 3, p4791 

    A review of the surface plasmon resonance (SPR) transducers based on tapered fibers that have been developed in the last years is presented. The devices have proved their good performance (specifically, in terms of sensitivity) and their versatility and they are a very good option to be...

  • 30 Years of Surface Plasmon Resonance (SPR) for Biosensing. Geddes, Chris // Plasmonics;Aug2014, Vol. 9 Issue 4, p727 

    An introduction is presented which discusses various topics presented at a symposium held at the Nanyang Technological University in Singapore from November 5?7, 2013 including fundamentals of surface plasmon optics in biosensing, surface plasmon resonance (SPR) biosensing and plasmon excitation.

  • Real-time monitoring of biomolecular interactions in blood plasma using a surface plasmon resonance biosensor. Špringer, Tomáš; Piliarik, Marek; Homola, Jiří // Analytical & Bioanalytical Chemistry;Nov2010, Vol. 398 Issue 5, p1955 

    We report a novel approach to biosensor-based observations of biomolecular interactions which enables real-time monitoring of biomolecular interactions in complex media. This approach is demonstrated by investigating the interaction between the human chorionic gonadotropin (hCG) and its antibody...

  • On-line determination of 3,5,6-trichloro-2-pyridinol in human urine samples by surface plasmon resonance immunosensing. Mauriz, E.; Calle, A.; Manclús, J. J.; Montoya, A.; Lechuga, L. M. // Analytical & Bioanalytical Chemistry;Apr2007, Vol. 387 Issue 8, p2757 

    An immunochemical method for the analysis of 3,5,6-trichloro-2-pyridinol (TCP), a major urinary metabolite of chlorpyrifos, is developed using a surface plasmon resonance (SPR)-based biosensor. The stability of the assay was assessed by covalently linking the analyte derivative to a thin,...

  • Red blood cells do not attenuate the SPCE fluorescence in surface assays. Matveeva, Evgenia G.; Gryczynski, Ignacy; Barnett, Anne; Calander, Nils; Gryczynski, Zygmunt // Analytical & Bioanalytical Chemistry;Jul2007, Vol. 388 Issue 5/6, p1127 

    We describe the positive effect of surface plasmon-coupled fluorescence emission (SPCE) on the detection of a signal from a surface immunoassay in highly absorbing or/and scattering samples. A model immunoassay using fluorescently labeled anti-rabbit antibodies that bind to rabbit immunoglobulin...

  • Mapping the interaction site of prion protein and Sho. Wan Jiayu; Hao Zhu; Xu Ming; Wang Xiong; Wu Songbo; Song Bocui; Liu Wensen; Li Jiping; Meng Keying; Li Zhongyi; Gao Hongwei // Molecular Biology Reports;Jun2010, Vol. 37 Issue 5, p2295 

    The cellular prion protein (PrPC) is a highly conserved protein among mammals and is considered to have important cellular functions. Despite decades of intensive research, however, the physiological function of PrPC remains unclear. Sho (Shadoo, shadow of prion protein) and PrPC have similar...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics