TITLE

应用米索前列醇治疗妊高症产后出血的疗效观察

AUTHOR(S)
张华; 张红英; 袁宁霞; 车虹彩; 徐珊; 陈建设
PUB. DATE
June 2016
SOURCE
Progress in Modern Biomedicine;Jun2016, Vol. 16 Issue 18, p3508
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: To explore the effect of Misoprostol in treating postpartum hemorrhage caused by pregnancy-induced hypertension(PIH). Methods: We selected in our hospital 200 cases of PIH pregnant women with postpartum bleeding. They were divided randomly into observation group and control group, 100 patients in each group. After fetal childbirth, patients in control group had intramuscular injection of oxytocin, while patients in observation group had Misoprostol and uterus massage. Compare the average blood loss and blood pressure after treatment between the two groups. Results: The average blood loss before treatment in control group and observation group was respectively(623.2±45.8) mL and(630.0 ± 46.3) mL, P1 = 0.176. After treatment, the average blood loss was respectively(486.1±24.3) m L and(313.3±23.1) mL in control group and observation group. Compared with before treatment,maternal blood loss after treatment was decreased in two groups. The blood loss in observation group was less than in control group(P2 =0.026). The systolic blood pressure and diastolic blood pressure of patients in severe PIH state in control group were(170.1±6.7) mm Hg,(113.2±2.1) mm Hg, those of patients in medium state were(153.6±5.1) mm Hg,(104.5±5.3) mm Hg, and those of patients in mild state were(138.9±4.2) mm Hg,(93.2±2.0) mm Hg, respectively. The systolic blood pressure and diastolic blood pressure of patients in severe PIH state in observation group were(169.2 ±6.5) mm Hg,(114.4 ±2.5) mm Hg, those in medium state were(156.2 ±4.8) mm Hg,(105.9 ±4.9) mm Hg, and those in mild state were(140.2 ±4.4) mm Hg,(90.2 ±4.4) mm Hg, respectively. Under the corresponding condition, there were no statistical differences between two groups(P3=0.87, P4=0.88, P5=0.75, P6=0.83, P7=0.64, P8=0.92). The incidence rates of adverse reactions in control group and observation group were respectively 1.0%(1/100) and 2.0%(2/100), with no statistical difference(P 0.05). Conclusion: Misoprostol is effective, safe and convenient to treat postpartum hemorrhage caused by pregnancy-induced hypertension. It is worthy of further promotion.
ACCESSION #
118031472

 

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