TITLE

Relationship between Fluoroquinolone Use and Changes in Susceptibility to Fluoroquinolones of Selected Pathogens in 10 United States Teaching Hospitals, 1991--2000

AUTHOR(S)
Zervos, Marcus J.; Hershberger, Ellie; Nicolau, David R.; Ritchie, David J.; Blackner, Lori K.; Coyle, Elizabeth A.; Donnelly, Andrew J.; Eckel, Stephen F.; Eng, Robert H. K.; Hiltz, Alexandra; Kuyumjian, Arpi G.; Krebs, William; McDaniel, Angee; Hogan, Patricia; Lubowski, Teresa J.
PUB. DATE
December 2003
SOURCE
Clinical Infectious Diseases;12/15/2003, Vol. 37 Issue 12, p1643
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We retrospectively examined the relationship between fluoroquinolone use and the susceptibilities of 11 bacterial pathogens to fluoroquinolones in 10 US teaching hospitals from 1991 through 2000. Statistical significance was determined by 2-way analysis of variance, with the number of isolates tested each year as a weighting factor. The analysis of baseline-to-end point change in the percentage of susceptibility and the slope of the regression line (trend line) for logit percentage of susceptibility showed that the overall percentage of susceptibility to fluoroquinolones decreased significantly during the study period (P < .05) and that change in percentage of susceptibility was significantly related to change in fluoroquinolone use (P < .05). Particularly notable were the decreases in the susceptibilities of Pseudomonas aeruginosa, Proteus mirabilis, and Escherichin coli (decreases of 25.1%, 11.9%, and 6.8%, respectively).
ACCESSION #
11768853

 

Related Articles

  • Survival of human pathogenic bacteria in different types of natural mineral water. Serrano, Concepción; Romero, Margarita; Alou, Luis; Sevillano, David; Corvillo, Iluminada; Armijo, Francisco; Maraver, Francisco // Journal of Water & Health;Sep2012, Vol. 10 Issue 3, p400 

    The aim of this study was to determine the survival of human pathogens (Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa) in five natural mineral waters (NMWs) with different properties and mineralization levels. Five NMWS from four Spanish spas with different dry residue at...

  • Bacteriological Pattern of Wound Swab Isolates in Patients with Chronic Leg Ulcer. Fadeyi, Abayomi; Adigun, Ismaila A.; Rahman, Ganiyu A. // International Journal of Health Research;Dec2008, Vol. 1 Issue 4, p183 

    PURPOSE: To determine the pattern of bacterial pathogens and their antibiotic sensitivity profile in patients with infected chronic leg ulceration. METHODS: Sixty swab specimens obtained from chronic leg ulcer (CLU) patients were cultured aerobically and the antibiotic sensitivity pattern of the...

  • Studies on Analysis of few secondary metabolites and antimicrobial activity of Ganoderma lucidum. Sakthivigneswari, G.; Dharmaraj, K. // Journal of Pharmacy Research;Aug2013, Vol. 6 Issue 8, p781 

    Objective: To evaluate the phytochemical studies and antimicrobial activity study the secondary metabolites of Ganoderma lucidum using HPTLC analysis and also assess the antimicrobial activity of selected mushroom against the selected pathogens of Escherichia coli, Pseudomonas aeruginosa,...

  • Characterization of the Alanine Racemases from Pseudomonas aeruginosa PAO1. Strych, Ulrich; Huang, Hung-Chung; Krause, Kurt L.; Benedik, Michael J. // Current Microbiology;Oct2000, Vol. 41 Issue 4, p290 

    Alanine racemases are ubiquitous, almost uniquely prokaryotic enzymes catalyzing the racemization between l- and d-alanine. The requirement for d-alanine as a necessary component of the bacterial cell wall makes this class of enzymes a logical target for the development of novel antibiotics. In...

  • Antibacterial Effect of Bovine Lactoferrin Against Udder Pathogens. Kutila, T.; Py�r�l�, S.; Saloniemi, H.; Kaartinen, L. // Acta Veterinaria Scandinavica;2003, Vol. 44, p35 

    The antibacterial effect of lactoferrin (Lf) was tested on isolates of Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and coagulase-negative staphylococci (CNS) as well as on Pseudomonas aeruginosa (P. aeruginosa) and Klebsiella pneumoniae (K. pneumoniae), originally isolated...

  • ANTAGONISTIC BACTERIA FROM LIVE CORALS, TUTICORIN COASTAL WATERS, SOUTHEASTERN INDIA.  // Pakistan Journal of Pharmaceutical Sciences;Apr2011, Vol. 24 Issue 2, p175 

    No abstract available.

  • Antibacterial Activities of Green Mussel (Perna viridis) and Edible Oyster (Crassostrea madrasensis). Annamalai, N.; Anburaj, R.; Jayalakshmi, S.; Thavasi, R. // Research Journal of Microbiology;2007, Vol. 2 Issue 12, p978 

    In the present study water, ethanol, methanol, acetone, hexane and butanol extracts of two Bivalves, Perna viridis and Crassostrea madrasensis were screened for antibacterial activity. The extracts were obtained from whole body tissue of the animals and tested against 10 different pathogenic...

  • Betaine aldehyde dehydrogenase from Pseudomonas aeruginosa: cloning, over-expression in Escherichia coli, and regulation by choline and salt. Velasco-García, Roberto; Villalobos, Miguel Angel; Ramírez-Romero, Miguel A.; Mújica-Jiménez, Carlos; Iturriaga, Gabriel; Muñoz-Clares, Rosario // Archives of Microbiology;Jan2006, Vol. 185 Issue 1, p14 

    In the human pathogen Pseudomonas aeruginosa, betaine aldehyde dehydrogenase (BADH) may play a dual role assimilating carbon and nitrogen from choline or choline precursors—abundant at infection sites—and producing glycine betaine, which protects the bacteria against the...

  • In vitro inhibitory effect of cranberry ( Vaccinium macrocarpum Ait.) juice on pathogenic microorganisms. Magariños, H.; Sahr, C.; Selaive, S.; Costa, M.; Figuerola, F.; Pizarro, O. // Applied Biochemistry & Microbiology;May2008, Vol. 44 Issue 3, p300 

    The purpose of this study was to determine the inhibitory effects of cranberry juice on pathogenic microorganisms. The microorganisms analyzed were Escherichia coli from patients with urinary infections, Salmonella spp., Listeria monocytogenes, Pseudomona aeruginosa, and Staphylococcus aureus....

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics