SUNCT syndrome secondary to prolactinoma

Matharu M S; Levy M J; Merry R T; Goadsby P J
November 2003
Journal of Neurology, Neurosurgery & Psychiatry;Nov2003, Vol. 74 Issue 11, p1590
Academic Journal
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome is a rare form of primary headache disorder, although secondary causes, particularly posterior fossa abnormalities, are well known. We report a case of SUNCT syndrome secondary to a prolactinoma. Administration of dopamine agonists led to complete resolution of the SUNCT attacks. This case, together with other similar case reports in the literature, highlight the importance of excluding a diagnosis of pituitary adenoma in all suspected cases of SUNCT syndrome, especially as the headache can precede more classical pituitary symptoms by a considerable period of time. Clinicians managing patients with suspected SUNCT syndrome should elicit a history of symptoms associated with pituitary neoplasms, perform a magnetic resonance imaging scan of the brain and pituitary, and screen for serum hormonal abnormalities.


Related Articles

  • Acute Tumor Response to ZD6126 Assessed by Intrinsic Susceptibility Magnetic Resonance Imaging. Robinson, Simon P.; Kalber, Tammy L.; Howe, Franklyn A.; McIntyre, Dominick J. O.; Griffiths, John R.; Blakey, David C.; Whittaker, Lynsey; Ryan, Anderson J.; Waterton, John C. // Neoplasia;May2005, Vol. 7 Issue 5, p466 

    The effective magnetic resonance imaging (MRI) transverse relaxation rate R2* was investigated as an early acute marker of the response of rat GH3 prolactinomas to the vascular-targeting agent, ZD6126. Multigradient echo (MGRE) MRI was used to quantify R2*, which is sensitive to tissue...

  • Ectopic prolactinoma within the sphenoidal sinus associated with empty sella. Ajler, Pablo; Bendersky, Damián; Hem, Santiago; Campero, Alvaro // Surgical Neurology International;2012, Vol. 3 Issue 1, p260 

    Background: Pituitary adenomas are a common cause of endocrinal dysfunction, which comprise 10-20% of all intracranial tumors. Although almost all of them arise within the sella turcica, there are some rare cases in which a pituitary adenoma is located outside the intrasellar region, so it is...

  • Endocrinological Outcome Following First Time Transsphenoidal Surgery for GH-, ACTH-, and PRL-Secreting Pituitary Adenomas. Kristof, R. A.; Schramm, J.; Redel, L.; Neuloh, G.; Wichers, M.; Klingmüller, D. // Acta Neurochirurgica;Jun2002, Vol. 144 Issue 6, p555 

    Summary. Background: To study remission rates and pituitary functions following transsphenoidal surgery of newly diagnosed GH-, ACTH-, and PRL-secreting pituitary adenomas. Methods: Out of a series of 329 newly diagnosed pituitary adenomas, 131 (39.8%) were hormone (67 GH-, 27 ACTH-, 37 PRL-)...

  • Positive Prolactin Response to Bromocriptine in 2 Patients with Cabergoline-Resistant Prolactinomas. Iyer, Pallavi; Molitch, Mark // Endocrine Practice;May2011, Vol. 17 Issue 3, pe55 

    Objective: To describe a positive prolactin response to bromocriptine treatment in 2 patients with cabergoline-resistant prolactinomas.Methods: We report the patients'' clinical presentations, laboratory test results, imaging findings, and clinical courses.Results: Patient 1 had a 5-mm pituitary...

  • Massive reduction of tumour load and normalisation of hyperprolactinaemia after high dose cabergoline in metastasised prolactinoma causing thoracic syringomyelia. van Uum, S. H. M.; van Alfen, N.; Wesseling, P.; van Lindert, E.; Pieters, G. F. F. M.; Nooijen, P.; Hermus, A. R. M. M. // Journal of Neurology, Neurosurgery & Psychiatry;Oct2004, Vol. 75 Issue 10, p1489 

    In 1970 a 20 year old woman presented with a pituitary chromophobe adenoma for which she underwent transfrontal pituitary surgery. In 1978 she had to be reoperated on because of local tumour recurrence, resulting in hypopituitarism. Bromocriptine (5 mg/day) was given for 15 years, but the plasma...

  • Posters.  // Neurological Sciences;Feb2012, Vol. 33, p215 

    No abstract available.

  • Acute shrinkage of a giant prolactinoma, masquerading as an erosive skull base tumour, with cabergoline. Dash, S.; Annamalai, A.K.; Simpson, H.L.; Sarkies, N.; Antoun, N.M.; Mannion, R. // QJM: An International Journal of Medicine;Jan2013, Vol. 106 Issue 1, p85 

    No abstract available.

  • Cluster Headache and Pituitary Prolactinoma. Edvardsson, Bengt // Journal of Medical Cases;2013, Vol. 4 Issue 8, p523 

    Cluster headache (CH) is a primary headache by definition not caused by any known underlying structural pathology. However, symptomatic cases have been described, for example, tumors, particularly pituitary adenomas, malformations, and infections/inflammations. The evaluation of CH is an issue...

  • Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion. Levy, M. J.; Robertson, I.; Howlett, T. A. // Case Reports in Neurological Medicine;2012, p1 

    We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics