TITLE

Parkinson's disease patients undershoot target size in handwriting and similar tasks

AUTHOR(S)
Van Gemmert A W A; Adler C H; Stelmach G E; Van Gemmert, A W A; Adler, C H; Stelmach, G E
PUB. DATE
November 2003
SOURCE
Journal of Neurology, Neurosurgery & Psychiatry;Nov2003, Vol. 74 Issue 11, p1502
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Objectives: Previous research suggested that people with Parkinson's disease are able to increase handwriting stroke size up to 1.5 cm without an increase of stroke duration; whereas age matched individuals in normal health are able to modulate stroke size without changes in stroke duration for sizes up to 2 cm. This study was designed to test this finding by examining whether sizes larger than 1.5 cm show different relationships with stroke duration for patients with Parkinson's disease as compared with age matched controls.Methods: The study included 13 subjects with Parkinson's disease and 13 age matched controls. Participants were required to write a cursive "llllllll" pattern, or a cursive "lililili" pattern without the dots, at a comfortable speed and also as fast as possible, in five different sizes (1.0, 1.5, 2.0, 3.0, and 5.0 cm). The participants wrote with a ballpoint pen on a digitiser tablet. The target pattern was displayed at its required size on a screen, but disappeared as soon as the pen touched the surface of the digitiser tablet. Online visual monitoring of the hand was prevented by a cover over the digitiser. After each trial, the recorded movement of the tip of the pen was displayed with two lines to indicate whether the size requirement had been met. The writing conditions were presented in random order and consisted of 12 trials for each participant.Results: The results demonstrated that stroke size and duration produced by the participants with Parkinson's disease were independently modulated up to 1.5 cm; sizes over 1.5 cm resulted in progressive undershooting by patients with Parkinson's disease (PD). It was also shown that these participants modulated acceleration measures inefficiently as compared with controls.Conclusions: The findings suggest that individuals with Parkinson's disease writing at speed produce inadequate stroke sizes when these should equal or exceed 1.5 cm.
ACCESSION #
11582841

 

Related Articles

  • Vascular parkinsonism. Sibon, Igor; Fenelon, Gilles; Quinn, Niall P.; Tison, François // Journal of Neurology;May2004, Vol. 251 Issue 5, p513 

    The concept of vascular parkinsonism (VP) has been highly controversial since the initial paper by Critchley in 1929. This review tentatively delineates the extent of the spectrum of VP. Much confusion has arisen owing to the lack of clear definitions of parkinsonism, “atypical...

  • Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings. Oblak, Adrian; Hagen, Matthew; Sweadner, Kathleen; Haq, Ihtsham; Whitlow, Christopher; Maldjian, Joseph; Epperson, Francine; Cook, Jared; Stacy, Mark; Murrell, Jill; Ozelius, Laurie; Brashear, Allison; Ghetti, Bernardino // Acta Neuropathologica;Jul2014, Vol. 128 Issue 1, p81 

    Rapid-onset dystonia-parkinsonism (RDP) is a movement disorder associated with mutations in the ATP1A3 gene. Signs and symptoms of RDP commonly occur in adolescence or early adulthood and can be triggered by physical or psychological stress. Mutations in ATP1A3 are also associated with...

  • parkinsonism. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p589 

    An encyclopedia entry for "parkinsonism" is presented. It refers to any neurological disorder. Parkinsonism is characterized by tremor, slow movements and rigidity. Causes of the disorder include cerebrovascular disease, the use of antipsychotic drugs, carbon monoxide poisoning and the infection...

  • Atypical parkinsonism in Guadeloupe: a common risk factor for two closely related phenotypes? Annie Lannuzel; G. U. Höglinger; S. Verhaeghe; L. Gire; S. Belson; M. Escobar-Khondiker; P. Poullain; W. H. Oertel; E. C. Hirsch; B. Dubois; M. Ruberg // Brain: A Journal of Neurology;Mar2007, Vol. 130 Issue 3, p816 

    In Guadeloupe, there is an abnormally high frequency of atypical parkinsonism. Only one-third of the patients that develop parkinsonian symptoms were reported to present the classical features of idiopathic Parkinson disease and one-third a syndrome resembling progressive supranuclear palsy...

  • Managing Parkinson's disease. Robinson, Gina // Independent Nurse;2/15/2010, p21 

    The article discusses Parkinson's disease, which is a degenerative neurological disease that affects 120,000 individuals in Great Britain aged 55-60 years old. Unilateral resting tremors, slowness and poor balance are among the symptoms of Parkinson's disease and its diagnosis is usually based...

  • The L-dopa response in vascular parkinsonism. Zijlmans J C M; Katzenschlager R; Daniel S E; Lees A J L; Zijlmans, J C M; Katzenschlager, R; Daniel, S E; Lees, A J L // Journal of Neurology, Neurosurgery & Psychiatry;Apr2004, Vol. 75 Issue 4, p545 

    Objective: To determine whether a positive L-dopa response in vascular parkinsonism (VP) is correlated with the presence of nigrostriatal pathology due to either vascular damage or neuronal cell loss.Methods: Seventeen patients with pathologically confirmed VP were...

  • Timing the initiation of treatment in Parkinson's disease. Grosset, Donald G.; Schapira, Anthony H. // Journal of Neurology, Neurosurgery & Psychiatry;Jun2008, Vol. 79 Issue 6, p615 

    The article presents views and insights of the author concerning the timing in the initiation of treatment in Parkinson's disease (PD). Clinical, imaging and pathological studies suggest that the cell loss begins 7 to 10 years before the onset of clinical features sufficient to allow the...

  • The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson’s disease. D Aarsland // Journal of Neurology, Neurosurgery & Psychiatry;Aug2009, Vol. 80 Issue 8, p928 

    BACKGROUND: Neuropsychiatric symptoms are common in Parkinson’s disease (PD) and have important clinical consequences for patients, caregivers and society. Few studies of neuropsychiatric symptoms in early untreated PD exist. OBJECTIVE: To explore the range, clustering and correlates of...

  • Spatial distribution of Parkinson's disease mortality in Spain, 1989-1998, as a guide for focused aetiological research or health-care intervention. de Pedro-Cuesta, Jesús; Rodríguez-Farré, Eduard; Lopez-Abente, Gonzalo // BMC Public Health;2009, Vol. 9 Issue 1, p445 

    Background: Aetiologically, genetic and environmental factors having an uneven spatial distribution may underlie Parkinson's disease (PD). Undiagnosis of PD in selected regions might have limited access to treatment with levodopa and simultaneously, if present at death, determined PD...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics