Combined field-induced dielectrophoresis and phase separation for manipulating particles in microfluidics

Bennett, Dawn J.; Khusid, Boris; James, Conrad D.; Galambos, Paul C.; Okandan, Murat; Jacqmin, David; Acrivos, Andreas
December 2003
Applied Physics Letters;12/8/2003, Vol. 83 Issue 23, p4866
Academic Journal
Experiments were conducted in microfluidics equipped with dielectrophoretic gates arranged perpendicular to the flow. Under the action of a high-gradient ac field and shear, flowing suspensions were found to undergo a phase separation and to form a distinct front between the regions enriched with and depleted of particles. We demonstrate that this many-body phenomenon, which originates from interparticle electrical interactions, provides a method for concentrating particles in focused regions and for separating biological and nonbiological materials. The evolution of the particle patterns formation is well described by a proposed electrohydrodynamic model. © 2003 American Institute of Physics.


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