TITLE

Physiopathology of multiple sclerosis

AUTHOR(S)
Visconti, A.; Santucci, S.; Talamanca, L. Figà; Cannoni, S.; Ristori, G.; Salvetti, M.
PUB. DATE
December 2003
SOURCE
Neurological Sciences;Dec2003 Supplement 5, Vol. 24, ps287
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Pleiotropy and redundancy are distinctive elements of the immune response. Recent research into the inflammatory component of multiple sclerosis (MS) indicates that, as expected, pleiotropy and redundancy characterize various physiopathological mechanisms of the disease. A certain degree of redundancy is becoming apparent also as far as the degenerative component is concerned. Cumulatively, these data suggest that treatments that target single pathogenetic pathways are unlikely to provide a definitive solution. Combination therapies may offer, in principle, some advantage, although there is a need for more information on the aetiology of the disease.
ACCESSION #
11563866

 

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