Conventional cervical smears were better than monolayer cytology or human papillomavirus testing for detecting cervical neoplasia

November 2003
ACP Journal Club;Nov/Dec2003, Vol. 139 Issue 3, p79
Academic Journal
This article discusses whether monolayer cytology (MLC) or human papillomavirus (HPV) testing is more accurate than the conventional cervical smear (CCS) test for detecting cervical neoplasia in women referred for colposcopy or presenting for routine smears. 828 women who had been referred for colposcopy and 1757 women who presented for routine smears were chosen for the study. All women were evaluated by the 3 methods i.e. CCS test, MLC, and HPV testing, and by colposcopy followed by biopsy if abnormalities were detected. After the CCS test, the remaining portion of the sample was used for the monolayer slide and for HPV testing.


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