TITLE

Combining fasting plasma glucose and glycosylated hemoglobin improved the accuracy for detecting patients with diabetes: COMMENTARY

AUTHOR(S)
Leibovici, Leonard
PUB. DATE
November 2003
SOURCE
ACP Journal Club;Nov/Dec2003, Vol. 139 Issue 3, p78
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In the study by researchers S.S. Anand and colleagues, the overall sensitivity of fasting plasma glucose (FPG) for diagnosing diabetes was low (48%). In clinical practice, we prefer to know which patients with normal or impaired FPG have diabetes according to the oral glucose tolerance test (OGTT). Patients with cardiovascular risk factors and increased risk for mortality cluster in this group. If they have abnormal glucose metabolism, different follow-up and management may be required. Because of the burden of screening a large population we have no other choice, although in certain populations the FPG levels might miss a small percentage of patients with diabetes. Although the question about screening does not have clear-cut answers, some conclusions may be drawn: First, persons with normal or impaired FPG should be stratified according to their risk for diabetes. Factors to consider include ethnic origin, obesity, and family history. A formal index should be developed and validated for that purpose. Second, persons at high risk for diabetes and cardiovascular morbidity should be closely followed even if FPG is normal. Third, the decision to use OGTT, a combination of FPG values and HbA[sublc], or close follow-up depends on the local population, as well as the cost of the tests. Fourth, serious and continuous effort should be made in these patients to modify risk factors and maintain healthy lifestyles.
ACCESSION #
11533522

 

Related Articles

  • Reduction of Intestinal Electrogenic Glucose Absorption After Duodenojejunal Bypass in a Mouse Model. Yan, Sheng; Sun, Fei; Li, Zhiwei; Xiang, Jie; Ding, Yuan; Lu, Zhongjie; Tian, Yang; Chen, Hui; Zhang, Jinhua; Wang, Yan; Song, Penghong; Zhou, Lin; Zheng, Shusen // Obesity Surgery;Sep2013, Vol. 23 Issue 9, p1361 

    Background: The role of intestinal glucose absorption in reducing glycemic levels after duodenojejunal bypass (DJB) is unclear. We hypothesized that DJB surgery decreases intestinal electrogenic glucose absorption by sodium glucose co-transporter 1 (SGLT1), leading to decreased glucose...

  • Tests of Glycemia in Diabetes. Goldstein, David E.; Little, Randie R.; Lorenz, Rodney A.; Malone, John I.; Nathan, David; Peterson, Charles M.; Sacks, David B. // Diabetes Care;Jul2004, Vol. 27 Issue 7, p1761 

    Summarizes current knowledge about tests used widely in monitoring the glycemic status of people with diabetes. Conceptual framework; Terminology; Historical perspective.

  • Prevalence of diabetes and predictions of its risks using anthropometric measures in southwest rural areas of China. Xiaolong Zhao; Xiaoming Zhu; Hengsheng Zhang; Weiwei Zhao; Jinhui Li; Yonghui Shu; Songwu Li; Minghui Yang; Linghu Cai; Jiping Zhou; Yiming Li // BMC Public Health;2012, Vol. 12 Issue 1, p821 

    Background: To examine the prevalence of diabetes and prediabetes in Songming county, Yunnan province, South-west China and examine influences of anthropometric indicators on diabetic risk. Methods: This study was a population based cross-sectional study of 1031 subjects in Songming County aged...

  • Effect of Feeding High-Fat with or Without Sucrose on the Development of Diabetes in Wistar Rats. Sivabalan, S.; Menon, Venugopal P. // Asian Journal of Biochemistry;2008, Vol. 3 Issue 5, p271 

    The aim of the study is to know the effect of high-fat and sucrose in the development of type 2 diabetes in Wistar rats. Several factors including high caloric diets,chronic positive caloric balance and the sedentary lifestyles are proposed as the causative factors in the development of type 2...

  • Battling with Rising Prevalence of Gestational Diabetes Mellitus: Screening and Diagnosis. Divakar, Hema; Manyonda, Issac // International Journal of Infertility & Fetal Medicine;Sep-Dec2011, Vol. 2 Issue 3, p96 

    Introduction: Gestational diabetes affects 2 to 4% of all pregnancies, with an increased risk of developing diabetes for both the mother and the child. The prevalence of gestational diabetes mellitus (GDM) in India varied from 3.8 to 21% with the geographical locations and diagnostic methods...

  • Predictive Parameters of Gestational Diabetes Mellitus. Crnčević-Orlić, Željka; Ružić, Alen; Miletić, Bojan; Petrović, Oleg; Zaputović, Luka; Kehler, Tatjana; Rački, Sanjin; Kapović, Miljenko // Collegium Antropologicum;Sep2007, Vol. 31 Issue 3, p771 

    Gestational diabetes mellitus is a carbohydrate intolerance recognized in pregnancy. The objective of this study was to determine the prevalence of gestational diabetes mellitus (GDM) of all deliveries at the University Hospital Rijeka, Croatia (34 997 deliveries over 10-year period) using...

  • The Road to Diabetes. Eberstein, Jacqueline A. // Diabetes Health;Jan2006, Vol. 15 Issue 1, p26 

    Discusses the stages in the development and progression of diabetes. Description of the glucose tolerance test; Health risks of high insulin levels; Impact of abnormal blood-test result on patients.

  • A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation. Haidinger, Michael; Werzowa, Johannes; Voigt, Hans-Christian; Pleiner, Johannes; Stemer, Gunar; Hecking, Manfred; Döller, Dominik; Hörl, Walter H.; Weichhart, Thomas; Säemann, Marcus D. // Trials;2010, Vol. 11, p91 

    Background: New-onset diabetes mellitus after transplantation (NODAT), a frequent and serious complication after transplantation, is associated with decreased graft and patient survival. Currently, it is diagnosed and treated primarily according to existing guidelines for type II diabetes. To...

  • FASTING PLASMA GHRELIN LEVELS ARE REDUCED, BUT NOT SUPPRESSED DURING OGTT IN OBESE AFRICAN AMERICAN ADOLESCENTS. Fluitt, Maurice B.; Gambhir, Kanwal K.; Nunlee-Bland, Gail; Odonkor, Wolali // Ethnicity & Disease;Autumn2013, Vol. 23 Issue 4, p436 

    Objective: Our study aimed to evaluate total plasma ghrelin (TGh) concentration and its correlation with leptin and insulin in obese African American (AA) adolescents with a family history of type 2 diabetes. Participants and Methods: Insulin, leptin, and TCh were measured for 15 non-obese...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics