Combining fasting plasma glucose and glycosylated hemoglobin improved the accuracy for detecting patients with diabetes

November 2003
ACP Journal Club;Nov/Dec2003, Vol. 139 Issue 3, p78
Academic Journal
This article discusses whether combination of fasting plasma glucose (FPG) and glycosylated hemoglobin is more accurate than FPG alone for diagnosing impaired glucose tolerance (IGT) and diabetes. The 1998 WHO diagnostic criteria were used as the gold standard to classify the participants into 3 categories: normal (FPG< 7.0 mmol/L and a 2-h glucose< 7.8 mmol/L), IGT (FPG< 7.0 mmol/L and a 2-h glucose 7.8 to 11.0 mmol/L), or diabetic (FPG≥ 7.0 mmol/L or a 2-hour glucose≥ 11.1 mmol/L). The American Diabetes Association criteria were also applied, and participants were classified into the 3 categories: normal (FPG< 6.1 mmol/L), impaired fasting glucose (FPG 6.1 to 6.9 mmol/L), or diabetic (FPG≥ 7.0 mmol/L).


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