Review: Rosiglitazone or pioglitazone as add-on therapy is effective for glycemic control in type 2 diabetes

November 2003
ACP Journal Club;Nov/Dec2003, Vol. 139 Issue 3, p67
Academic Journal
This article discusses whether rosiglitazone or pioglitazone is more effective than other anti-diabetic agents when used either as monotherapy or add-on therapy in patients with type 2 diabetes mellitus. Studies were selected if they were randomized controlled trials comparing rosiglitazone or pioglitazone, as monotherapy or as add-on therapy, with other anti-diabetic agents in patients greater than 18 years of age with type 2 diabetes. The main outcomes were mean differences from baseline to endpoint in glycosylated hemoglobin and fasting plasma glucose levels.


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