Hospital Transmission of Community-Acquired Methicillin-Resistant Staphylococcus aureus among Postpartum Women

Saiman, Lisa; O'Keefe, Mary; Graham III, Philip L.; Fann Wu, Philip L.; Saïd-Salim, Battouli; Kreiswirth, Barry; LaSala, Anita; Schlievert, Patrick M.; Della-Latta, Phyllis
November 2003
Clinical Infectious Diseases;11/15/2003, Vol. 37 Issue 10, p1313
Academic Journal
Infections caused by community-acquired methicillin­resistant Staphylococcus aureus (CA-MRSA) are being increasingly observed in patients who lack traditional risk factors. We described 8 postpartum women who developed skin and soft-tissue infections caused by MRSA at a mean time of 23 days (range, 4—73 days) after delivery. Infections included 4 cases of mastitis (3 of which progressed to breast abscess), a postoperative wound infection, cellulitis, and pustulosis. The outbreak strains were compared with the prototype CA-MRSA strain MW2 and found to be indistinguishable by pulsed-field gel electrophoresis. All were spa type 131, all contained the staphylococcal chromosomal cassette mec type IV, and all expressed Panton­Valentine leukocidin and staphylococcal enterotoxins C and H. The route of transmission was not discovered: the results of surveillance cultures of samples obtained from employees of the hospital, the hospital environment, and newborns were negative for the outbreak strain. We report that MW2, which was previously limited to the midwestern United States, has spread to the northeastern United States and has become a health care­associated pathogen.


Related Articles

  • Population-Based Study of the Epidemiology of and the Risk Factors for Invasive Staphylococcus aureus Infections. Laupland, Kevin B.; Church, Deidre L.; Mucenski, Melissa; Sutherland, Lloyd R.; Davies, H. Dele // Journal of Infectious Diseases;5/1/2003, Vol. 187 Issue 9, p1452 

    Defines the epidemiology of invasive Staphylococcus aureus infections, using results from a population-based active-surveillance study of the Calgary Health Region, conducted from May 1999 to April 2000. Classification of the annual incidence; Tendency for infection to be common in people at...

  • Health care-associated MRSA declining.  // Infectious Disease News;Sep2010, Vol. 23 Issue 9, p20 

    The article focuses on a study which revealed that the incidence of hospital-onset invasive methicillin-resistant Staphylococcus aureus (MRSA) is declining.

  • CA-MRSA may be increasing in incidence but decreasing in virulence.  // Infectious Disease News;Apr2009, Vol. 22 Issue 4, p20 

    The article discusses the findings of a study presented at the 2009 meeting of the Society for Healthcare Epidemiology of America in the U.S., which revealed that the proportion of methicillin-resistant Staphylococcus aureus (MRSA) blood stream infections increased from 2000 to 2005, but...

  • Nasal Carriage ofStaphylococcus aureusand Prevention of Nosocomial Infections. Kluytmans, J.; Wertheim, H. // Infection;Feb2005, Vol. 33 Issue 1, p3 

    This review summarizes the clinically relevant aspects of nasal carriage ofStaphylococcus aureus. The epidemiology, associated risk, and the effects of eradication are discussed. The main conclusions are that nasal carriage ofS. aureusis a well-defined risk factor for subsequent infection in...

  • Antibiotic use linked to MRSA risk.  // Infectious Diseases in Children;Dec2008, Vol. 21 Issue 12, p32 

    The article discusses findings of a study presented by Rosie Lyles during the 2008 Interscience Conference on Antimicrobial Agents and Chemotherapy/Infectious Diseases Society of America Meeting, which examined predictors of methicillin-resistant Staphylococcus aureus (MRSA). The study revealed...

  • Invasive Methicillin-Resistant Staphylococcus aureus Infections Among Dialysis Patients -- United States, 2005. Collins, A.; Forrest, B.; Klevens, R. M.; Patel, P.; Arduino, M. J.; Fosheim, G.; Morrison, M.; Lucero, C. A. // MMWR: Morbidity & Mortality Weekly Report;3/9/2007, Vol. 56 Issue 9, p197 

    The article assesses the incidence of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections in dialysis patients in the U.S. in 2005. The author recognizes that dialysis patients are vulnerable to infections and commonly caused by methicillin-resistant Staphylococcus aureus. An...

  • ABSTRACTS. Kollins, S. H.; McClernon, F. J.; Fuemmeler, B. F.; Purcell, K.; Fergie, J.; Schroeder, A. R.; Newman, T. B.; Wasserman, R. C.; Gates, G. A.; Verrall, A. M.; Steele, S. R.; Martin, M. J.; Mullenix, P. S.; Saltzman, D. J.; Williams, R. A.; Gelfand, D. V.; Kivipelto, M.; Ngandu, T.; Fratiglioni, L.; Sirovich, B. E. // JAMA: Journal of the American Medical Association;12/28/2005, Vol. 294 Issue 24, p3067 

    The article consists of abstracts for published medical research. Topics include psychiatry, pediatric and adolescent medicine, surgery, neurology, internal medicine, ophthalmology, and otolaryncology. The studies include "Association Between Smoking and Attention-Deficit/Hyperactivity Disorder...

  • Managing MRSA. Breindl, Anette // BioWorld Today;2/14/2011, Vol. 22 Issue 30, Special section p2 

    The article reports on a study which identified a new way of stopping the growth of methicillin-resistant Staphylococcus aureus (MRSA).

  • The causative agents in infective endocarditis: a systematic review comprising 33,214 cases. Vogkou, Christiana; Vlachogiannis, Nikolaos; Palaiodimos, Leonidas; Kousoulis, Antonis // European Journal of Clinical Microbiology & Infectious Diseases;Aug2016, Vol. 35 Issue 8, p1227 

    Infective endocarditis (IE) incidence remains high with considerable fatality rates; guidelines for prophylaxis against IE are currently under review in some settings which highlights the importance of maintaining up-to-date epidemiological estimates about the most common microbial causes. The...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics