SIGNAL PROCESSING: Closing the gap

Jones, Rachel
October 2001
Nature Reviews Neuroscience;Oct2001, Vol. 2 Issue 10, p680
Academic Journal
Discusses a study which demonstrated that axons of hippocampal neurons are electrically coupled by gap junctions. Information on spikelets; Evidence of axo-axonal gap junctions; Function of axo-axonal coupling.


Related Articles

  • Activation of an Inwardly Rectifying K[sup +] Conductance by Orphanin-FQ/Nociceptin in Vasopressin-Containing Neurons. Slugg, Robert M.; Rønnekleiv, Oline K.; Grandy, David K.; Kelly, Martin J. // Neuroendocrinology;1999, Vol. 69 Issue 5, p385 

    The orphanin-FQ/nociceptin (OFQ/N) receptor (previously, ORL[sub 1] , LC132) has been shown to be coupled to an inwardly rectifying K[sup +] conductance in several neuronal populations. Although OFQ/N receptor mRNA is densely expressed in the supraoptic nucleus (SON), little is known about its...

  • Current Literature Gap Junctions in Epileptogenesis: Chicken or Egg? Benardo, Larry S. // Epilepsy Currents;Mar/Apr2004, Vol. 4 Issue 2, p80 

    Comments on the study "Epileptiform Activity in Hippocampal Slice Cultures Exposed Chronically to Bicuculline: Increased Gap-Junctional Function and Expression," by M. Samoilova, J. Li, M. R. Pelletier, K. Wentlandt, Y. Adamchik, C. C. Naus and P. L. Carlen, which examined the influence of...

  • Fast Ripples: What Do New Data about Gap Junctions and Disrupted Spike Firing Reveal about Underlying Mechanisms? Ben-Ari, Yehezkel // Epilepsy Currents;Mar/Apr2009, Vol. 9 Issue 2, p57 

    Gap junctions have been postulated to exist between the axons of excitatory cortical neurons based on electrophysiological, modeling, and dye-coupling data. Here, we provide ultrastructural evidence for axoaxonic gap junctions in dentate granule cells. Using combined confocal laser scanning...

  • Analysis of connexin expression during seizures induced by 4-aminopyridine in the rat hippocampus. Laura, Medina-Ceja; Xóchitl, Flores-Ponce; Anne, Santerre; Alberto, Morales-Villagrán // Journal of Biomedical Science;Aug2015, Vol. 22 Issue 1, p1 

    Background: In epilepsy, seizures are generated by abnormal synchronous activity in neurons. In the rat hippocampus (HIP), epileptiform activity has been found to be associated with gap junctions (GJs). GJs are formed by the combination of two hemichannels, each composed of six connexins. At low...

  • Shaping bursting by electrical coupling and noise. Medvedev, Georgi; Zhuravytska, Svitlana // Biological Cybernetics;Feb2012, Vol. 106 Issue 2, p67 

    Gap-junctional coupling is an important way of communication between neurons and other excitable cells. Strong electrical coupling synchronizes activity across cell ensembles. Surprisingly, in the presence of noise synchronous oscillations generated by an electrically coupled network may differ...

  • nexus.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1584 

    An encyclopedia entry for "nexus," which refers to a bond between components of a group, is presented.

  • Adult Rat Motor Neurons Do Not Re-Establish Electrical Coupling during Axonal Regeneration and Muscle Reinnervation. Favero, Morgana; Cangiano, Alberto; Busetto, Giuseppe // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1 

    Gap junctions (GJs) between neurons are present in both the newborn and the adult nervous system, and although important roles have been suggested or demonstrated in a number of instances, in many other cases a full understanding of their physiological role is still missing. GJs are expressed in...

  • Intercellular calcium signalling in cultured renal epithelia: a theoretical study of synchronization mode and pacemaker activity. De Blasio, Birgitte Freiesleben; Iversen, Jens-Gustav; Røttingen, John-Arne // European Biophysics Journal;2004, Vol. 33 Issue 8, p657 

    We investigate a two-dimensional lattice model representation of intercellular Ca2+ signalling in a population of epithelial cells coupled by gap junctions. The model is based on and compared with Ca2+ imaging data from globally bradykinin-stimulated MDCK-I (Madin-Darby canine kidney)-I cell...

  • Expression of connexin genes in the human retina. Söhl, Goran; Joussen, Antonia; Kociok, Norbert; Willecke, Klaus // BMC Ophthalmology;2010, Vol. 10, p27 

    Background: Gap junction channels allow direct metabolically and electrical coupling between adjacent cells in various mammalian tissues. Each channel is composed of 12 protein subunits, termed connexins (Cx). In the mouse retina, Cx43 could be localized mostly between astroglial cells whereas...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics