Müller, Stefan; Hoege, Carsten; Pyrowolakis, George; Jentsch, Stefan
March 2001
Nature Reviews Molecular Cell Biology;Mar2001, Vol. 2 Issue 3, p202
Academic Journal
Covalent modification of cellular proteins by the ubiquitin-like modifier SUMO regulates various cellular processes, such as nuclear transport, signal transduction, stress response and cell-cycle progression. But, in contrast to ubiquitylation, sumoylation does not tag proteins for degradation, but seems to enhance their stability or modulate their subcellular compartmentalization.


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