TITLE

Assessment of atrial electromechanical interval and P wave dispersion in patients with polycystic ovary syndrome

AUTHOR(S)
Bayı, Pınar Türker; Güray, Ümit; Duyuler, Serkan; Demirkan, Burcu; Kayaalp, Oya; Kanat, Selçuk; Güray, Yeşim
PUB. DATE
February 2016
SOURCE
Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi;Feb2016, Vol. 16 Issue 2, p100
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective: Polycystic ovary syndrome (PCOS) is associated with increased cardiovascular risk, including ischemic stroke. Prolonged atrial electromechanical interval (EMI) is related to increased atrial fibrillation (AF) risk. The aim of the study is to evaluate atrial EMI and electrocar-diographic P-wave indices related to increased AF risk in patients with PCOS. Methods: Forty PCOS patients diagnosed on the basis of the Rotterdam criteria and 20 age-matched controls were prospectively included. patients with atrioventricular or intraventricular conduction abnormalities, dysrhythmia or taking antiarrhythmic drugs, atherosclerotic heart disease, cardiomyopathies, valvular lesions, pericardial disease, a history of pulmonary emboli or pulmonary hypertension, and abnormal thyroid function were excluded. Intra and interatrial EMI were measured by tissue Doppler imaging and P-wave dispersion (Pd) was calculated on 12-lead electrocardiography (ECG). The Isovolumetric relaxation time was the interval between the aortic valve closure artifact at the end of the LV outflow envelope and the mitral valve opening artifact at the beginning of the mitral E wave. Results: Patients with PCOS had significantly higher interatrial [38 (24-65) ms vs. 16 (9-19) ms p<0.001], left-sided intra-atrial (14.8±6.1 vs. 7±1.7 ms, p<0.001), and right-sided intra-atrial (22.3±8.1 vs. 8.6±3.6 ms, p<0.001) EMI compared with the control group. Pd was significantly greater in the PCOS group compared with control group [45 (27-60) ms vs. 30 (26-38) ms, p<0.001]. Echocardiographic parameters of atrial EMI were significantly correlated with body mass index, Pd, and isovolumetric relaxation time in patients with PCOS. Conclusion: PCOS is associated with prolonged inter- and intra-atrial conduction times, which are related to increased AF risk.
ACCESSION #
112972799

 

Related Articles

  • Insulin-like growth factor 1, liver enzymes, and insulin resistance in patients with PCOS and hirsutism. ÇAKIR, Evrim; TOPALOĞLU, Oya; BOZKURT, Nujen ÇOLAK; BAYRAKTAR, Başak KARBEK; GÜNGÜNES, Aşkin; ARSLAN, Müyesser SAYKI; ÜNSAL, İlknur ÖZTÜRK; TUTAL, Esra; UÇAN, Bekir; DELİBAŞI, Tuncay // Turkish Journal of Medical Sciences;2014, Vol. 44 Issue 5, p781 

    Aim: Hyperinsulinemia and insulin resistance are commonly seen in patients with hirsutism and polycystic ovary syndrome (PCOS), and are associated with cardiovascular disease risk. However, it is not yet known whether insulin-like growth factor I (IGF-I) and alanine transaminase (ALT) produced...

  • Raising awareness of polycystic ovary syndrome. Tomlinson, Julie; Letherby, Gayle; Pinkney, Jonathan; Millward, Ann; Stenhouse, Elizabeth // Nursing Standard;6/5/2013, Vol. 27 Issue 40, p35 

    Aim: To identify women's experience of receiving information about polycystic ovary syndrome (PCOS), and develop an information booklet. Method: Women from Cornwall with a diagnosis of PCOS participated in focus groups to discuss their experiences of the condition. Findings: Participants...

  • Microvascular dysfunction in women with polycystic ovary syndrome. K. Lakhani; A. Leonard; A.M. Seifalian; P. Hardiman // Human Reproduction;Nov2005, Vol. 20 Issue 11, p3219 

    BACKGROUND: Polycystic ovary syndrome (PCOS) is associated with multiple cardiovascular risk factors and an increased prevalence of arterial dysfunction. However, microvascular dysfunction in PCOS has not been assessed. METHODS: Subjects comprised 12 women with PCOS and 12 age-matched controls...

  • Black PCOS Women Have Higher Risk for Metabolic Syndrome and CVD than White PCOS Women.  // Fertility Weekly;5/12/2014, p7 

    The article discusses a study which aims to determine the risk of cardiovascular disease (CVD) and prevalence of metabolic syndrome (MetSyn) on African American and White American adolescents and adult women with polycystic ovary syndrome (PCOS). Results show higher prevalence of MetSyn among...

  • Glucose intolerance, insulin resistance and cardiovascular risk factors in first degree relatives of women with polycystic ovary syndrome. Murat Yılmaz; Neslihan Bukan; Reyhan Ersoy; Ayhan Karakoç; İlhan Yetkin; Göksun Ayvaz; Nuri Çakır; Metin Arslan // Human Reproduction;Sep2005, Vol. 20 Issue 9, p2414 

    BACKGROUND: The aim of the present study was to evaluate insulin resistance (IR), glucose tolerance status and cardiovascular risk factors in first degree relatives of patients with polycystic ovary syndrome (PCOS). METHODS: A total of 120 family members [MothersPCOS (n=40), FathersPCOS (n=38),...

  • ANDROGEN EXCESS AS A MAJOR DETERMINANT OF CARDIOVASCULAR RISK IN WOMEN: EVIDENCE FROM THE POLYCYSTIC OVARY SYNDROME. Pepene, C. E. Georgescu // Acta Endocrinologica (1841-0987);Oct-Dec2011, Vol. 7 Issue 4, p529 

    Apart from endocrine and reproductive disturbances, polycystic ovary syndrome (PCOS) clusters several cardiovascular risk factors, mainly insulin resistance, obesity and dyslipidemia. In addition, androgen excess significantly contributes to enhanced vascular risk. Several mediators of...

  • The effects of rosiglitazone and metformin on oxidative stress and homocysteine levels in lean patients with polycystic ovary syndrome. Murat Yilmaz; Neslihan Bukan; Göksun Ayvaz; Ayhan Karakoç; Füsun Törüner; Nuri Çakir; Metin Arslan // Human Reproduction;Dec2005, Vol. 20 Issue 12, p3333 

    BACKGOUND: Oxidative stress and hyperhomocysteinaemia are risk factors for cardiovascular diseases. The aim of this study was to assess the effects of rosiglitazone and metformin on cardiovascular disease risk factors such as insulin resistance, oxidative stress and homocysteine levels in lean...

  • New consensus statement on assessment of CV risk, prevention in women with PCOS. Brannon, Matthew // Endocrine Today;Jun2010 Supplement, Vol. 8, p13 

    The article emphasizes the need to assess the risk of cardiovascular disease in women with polycystic ovary syndrome (PCOS).

  • Metabolic syndrome in Greek women with polycystic ovary syndrome: prevalence, characteristics and associations with body mass index. A prospective controlled study. Kyrkou, Giannoula; Trakakis, Eftichios; Attilakos, Achilleas; Panagopoulos, Periklis; Chrelias, Charalampos; Papadimitriou, Anastasios; Vaggopoulos, Vasilis; Alexiou, Eleni; Mastorakos, Georgios; Lykeridou, Aikaterini; Kassanos, Dimitrios; Papaevangelou, Vasiliki; Papantoniou, Nikolaos // Archives of Gynecology & Obstetrics;Apr2016, Vol. 293 Issue 4, p915 

    Purpose: The aim of this study was to estimate the prevalence, to evaluate the characteristics of the metabolic syndrome (MetS) in Greek women with polycystic ovary syndrome (PCOS) and to investigate the correlation of MetS with body mass index (BMI).Methods: In a...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics