TITLE

Memory affected by single gene

PUB. DATE
October 2003
SOURCE
New Scientist;10/25/2003, Vol. 180 Issue 2418, p17
SOURCE TYPE
Periodical
DOC. TYPE
Article
ABSTRACT
A single gene has a profound effect on short-term memory skills, making a significant difference to how many words people can remember from a list. The neurotransmitter serotonin is best known for its role in depression, but drugs that block a particular serotonin receptor in the brain also inhibit short-term memory. People inherit one of two types of the gene for this receptor, with 9 per cent of people having a form that is less readily stimulated by serotonin.
ACCESSION #
11279144

 

Related Articles

  • Serotonin and NMDA glutamate receptor antagonists selectively impair the reactivation of associative memory in the common snail. S. Solntseva; V. Nikitin // Neuroscience & Behavioral Physiology;Sep2008, Vol. 38 Issue 7, p687 

    Abstract  Experiments on the common snail were performed to study the influences of serotonin and glutamate receptor antagonists on the processes of reactivation of an associative habit consisting of refusing a particular type of food. Twenty-four hours after training, animals...

  • Role of Serotonin in Alzheimer's Disease. Geldenhuys, Werner I.; Van der Schyf, Cornelis I. // CNS Drugs;2011, Vol. 25 Issue 9, p765 

    Mounting evidence accumulated over the past few years indicates that the neurotransmitter serotonin plays a significant role in cognition. As a drug target, serotonin receptors have received notable attention due in particular to the role of several serotonin-receptor subclasses in cognition and...

  • Changes in the Expression of Monoaminergic Genes under the Influence of Repeated Experience of Agonistic Interactions: From Behavior to Gene. Kudryavtseva, N. N.; Filipenko, M. L.; Bakshtanovskaya, I. V.; Avgustinovich, D. F.; Alekseenko, O. V.; Beilina, A. G. // Russian Journal of Genetics;Jun2004, Vol. 40 Issue 6, p590 

    The role of genetic and environmental factors as well as brain neurochemistry in regulating aggressive and submissive behaviors in animals are considered. We present a review of data on changes in brain monoaminergic activity (synthesis, catabolism, receptors) and on the expression of...

  • Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation. Bockaert, Joël; Claeysen, Sylvie; Bécamel, Carine; Dumuis, Aline; Marin, Philippe // Cell & Tissue Research;Oct2006, Vol. 326 Issue 2, p553 

    Serotonin (5-hydroxytryptamine, 5-HT) is, without doubt, the neurotransmitter for which the number of receptors is the highest. Fifteen genes encoding functional 5-HT receptors have been cloned in mammalian brain. 5-HT3 receptors are ionotropic receptors, whereas all the others are metabotropic...

  • Gαo and Gαq Regulate the Expression of daf-7, a TGFβ-like Gene, in Caenorhabditis elegans. Myers, Edith M. // PLoS ONE;Jul2012, Vol. 7 Issue 7, p1 

    Caenorhabditis elegans enter an alternate developmental stage called dauer in unfavorable conditions such as starvation, overcrowding, or high temperature. Several evolutionarily conserved signaling pathways control dauer formation. DAF-7/ TGFβ and serotonin, important ligands in these...

  • Differential Expression of the 5-HT and 5-HT Receptor in Differentiated NG108-15 Cells. Asano, Hajime; Miyamoto, Akinori; Nakao, Mariko; Wakaki, Chiyuki; Iida, Takuma; Funakami, Yoshinori; Wada, Tetsuyuki; Ichida, Seiji // Neurochemical Research;Aug2012, Vol. 37 Issue 8, p1738 

    Previous work from this laboratory has shown that the serotonin (5-HT) induced response is significantly augmented in differentiated NG108-15 (NG) cells treated with dibutyryl cAMP (BtcAMP) due to qualitative and quantitative changes in the expression of the 5-HT receptor as demonstrated by...

  • 5-hydroxytryptamine.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1108 

    An encyclopedia entry for the medical term "5-hydroxytryptamine," also known as serotonin, is presented.

  • Continuing Education Test #1141.  // RN;Aug2008, Vol. 71 Issue 8, p31 

    A quiz concerning serotonin syndrome is presented.

  • Expression of 5HT-1A and 5HT-1B Receptor Genes in Brains of Wistar-Zagreb 5HT Rats. Bordukalo-Nikšić, Tatjana; Mokrović, Gordana; Jernej, Branimir; Čičin-Šain, Lipa // Collegium Antropologicum;Jan2008 Supplement 1, Vol. 32, p37 

    By selective breeding, two sublines of rats with high or low activity of platelet serotonin (5HT) transporter (5HTt) have been developed (Wistar-Zagreb 5HT rats). Previous studies demonstrated significant differences between the sublines in the expression of platelet 5HTt at the level of both,...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics