TITLE

The regulatory effect of dipeptides on cell proliferation in mammalian nerve tissue culture and olfactory associative learning in insects

AUTHOR(S)
Chalisova, N.; Zachepilo, T.; Kamyshev, N.; Lopatina, N.
PUB. DATE
November 2015
SOURCE
Journal of Evolutionary Biochemistry & Physiology;Nov2015, Vol. 51 Issue 6, p495
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The study addresses the effects of dipeptides AspPro and AspSer and their constituent amino acids (aspartic acid-Asp, proline-Pro, and serine-Ser) on proliferative activity of rat brain cortical and subcortical tissue explants and functional activity of the honeybee central nervous system. The area index was calculated as a ratio of the total explant area to the area of its central zone. The number of bees which exhibited a conditioned response, namely proboscis extension towards the odorized solution, 1 min (short-term memory) and 180 min (long-term memory) after single trial learning was also measured. Both dipeptides, as well as aspartate itself, stimulated the expansion of the growth zone of rat subcortical tissue explants and increased the number of bees that retained in their short-term/long-term memory the acquired conditioned response, regardless of the effect of the second component of the dipeptide. The similarity of these effects suggests that common mechanisms of reception and signal transduction have evolved in insects and mammals, and this requires further study.
ACCESSION #
112692926

 

Related Articles

  • Subchronic Toxicity of Triethylenetetramine Dihydrochloride in B6C3F1 Mice and F344 Rats. GREENMAN, DAVID L.; MORRISSEY, ROBERT L.; BLAKEMORE, WILLIAM; CROWELL, JAMES; SIITONEN, PAUL; FELTON, PAUL; ALLEN, RICHARD; CRONIN, GERALD // Fundamental & Applied Toxicology;1996, Vol. 29 Issue 2, p185 

    Triethylenetetramine dihydrochloride (trien-2HCl; CAS No. 38260-01-04), a chelating agent used to treat Wilson's disease patients who are intolerant of the drug of choice, was tested for subchronic toxicity in B6C3F1 mice and F344 rats. Mice and rats received trien-2HCl in the drinking water at...

  • Formation and persistence of 8-oxoguanine in rat lung cells... Nehls, Peter; Seiler, Frank; Rehn, Bernd; Greferath, Ruth; Bruch, Joachim // Environmental Health Perspectives Supplements;Sep97 Supplement 5, Vol. 105, p1291 

    Investigates the effects of quartz (DQ12) and of the nontumorigenic dust corundum on the induction of 8-oxoguanine in the deoxyribonucleic acid (DNA) of rat lung cells and cell proliferation and pulmonary inflammation. Methodology used; Findings and analysis of results; Conclusions.

  • REDUNDANCIA DE LA INFORMACIÓN VISUAL EN EL CONDICIONAMIENTO AVERSIVO: PAPEL DEL COLÍCULO SUPERIOR. García, Misael F.; León, Laura A.; Cardenas, Fernando P. // Suma Psicológica;jun2009, Vol. 16 Issue 1, p9 

    A relevant feature of biological systems is the distributed processing. This kind of information processing ensures a functional redundancy that allows a functional level even in the absence of some regions of the system. In the case of visual system, the parallel processing relies on three...

  • THE PHILADELPHIA SYMPOSIUM ON AGING. Adelman, Richard C.; Cristofalo, Vincent J.; Roberts, Jay // BioScience;Mar1975, Vol. 25 Issue 3, p199 

    The article presents information related to the Symposium on Aging, which was held in Valley Forge, Pennsylvania from September 30, 1974 to October 2, 1974. It is informed that the symposium reviewed current knowledge of the potential importance of changes in cellular proliferation, the...

  • The functions and regulation of the PTEN tumour suppressor. Song, Min Sup; Salmena, Leonardo; Pandolfi, Pier Paolo // Nature Reviews Molecular Cell Biology;May2012, Vol. 13 Issue 5, p283 

    The importance of the physiological function of phosphatase and tensin homologue (PTEN) is illustrated by its frequent disruption in cancer. By suppressing the phosphoinositide 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) pathway through its lipid phosphatase activity, PTEN governs a...

  • WpÅ‚yw zmian hormonalnych okresu okoÅ‚omenopauzalnego u kobiet z Å‚uszczycÄ… na przebieg choroby i jakość życia. Makara-Studzińska, Marta; Lewicka, Magdalena; Pietrzak, Aldona; Sulima, Magdalena; Sosnowska, Katarzyna; Figurska, Agata; Bartosińska, Joanna; Paszkowski, Tomasz; Chodorowska, Grażyna // Dermatology Review / Przeglad Dermatologiczny;2013, Vol. 100 Issue 1, p48 

    The article presents the impact of hormonal changes that occur during perimenopause on the course of psoriasis and quality of life of women. Psoriasis is a chronic, inflammatory skin disease, a genetically determined condition characterized by benign proliferation of epidermal cells and the...

  • Preparation of Testicular Cell Conditioned Medium from Rat Testis. Mortazavi, M.; Mohammadi Roushandeh, A. // Cell Journal (Yakhteh);Summer 2013 Supplement 1, Vol. 15 Issue Sup 1, p62 

    Objective: In vivo, growth factors that mediate local cellcell interactions are responsible for the differentiation of primordial germ cells (PGCs) into germ stem cells after the arrival at the genital ridge. in vitro differentiation of PGCs is also dependent on their sequential exposure and...

  • Successful treatment of polymorphic post-transplant lymphoproliferative disorder after allo-HSCT with reduction of immunosuppression. Zhenyang Gu; Bo Cai; Lei Yuan; Honghua Li; Wenrong Huang; Yu Jing; Haiyan Zhu; Yu Zhao; Jian Bo; Quanshun Wang; Xiaoping Han; Li Yu; Chunji Gao // International Journal of Clinical & Experimental Medicine;2014, Vol. 7 Issue 7, p1904 

    Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication for recipients of solid organ transplantation (SOT) and allogeneic hematopoietic stem cell transplantation (allo-HSCT). In SOT recipients, who previously have a normal immune system that has been...

  • CHINA BIOTECHNOLOGY.  // Acquisdata Industry SnapShot: China - Biotechnology;10/2/2014, Issue 1943, preceding p1 

    The article offers news briefs on the Chinese biotechnology industry in 2014 including the appointment of William R. Keller to the research company WuXi Pharma Tech Board of Directors, Citreoviridin's inhibition of cell proliferation, and overview of pharmaceutical company Amoytop Biotech Co. Ltd.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics