TITLE

Stabilization of Homeostasis in Rats during Cold Exposure with Ethanol

AUTHOR(S)
Kolosova, O.; Kershengolts, B.
PUB. DATE
January 2016
SOURCE
Bulletin of Experimental Biology & Medicine;Jan2016, Vol. 160 Issue 3, p300
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The role of ethanol metabolism system in adaptation of laboratory animals to cold temperatures was shown. Cold stress (1-2°C) modeled in male Wistar rats over 7 weeks significantly modulated endogenous ethanol metabolism and led to reorganization of many physiological systems, which resulted in activation of metabolic processes. Under these conditions, endogenous ethanol was utilized as the most easily and fast metabolized energy substrate, due to which its blood concentration decreased and was replenished at the expense of exogenous ethanol. Normalization of blood ethanol concentration led to better adaptation to cold.
ACCESSION #
112294533

 

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