Successful weaning from inhaled nitric oxide using dipyridamole

Saiki, Yoshikatsu; Nitta, Yoshio; Tsuru, Yusuke; Tabayashi, Koichi
November 2003
European Journal of Cardio-Thoracic Surgery;Nov2003, Vol. 24 Issue 5, p837
Academic Journal
A 33-year-old woman with an atrial septal defect associated with severe pulmonary hypertension underwent suture closure of the defect after assessment of operability by lung biopsy. Postoperative course was complicated by suprasystemic refractory pulmonary hypertension, and she became dependent upon treatment with inhaled nitric oxide. After multiple attempts to withdraw nitric oxide, dipyridamole was administered and blunted the rebound pulmonary hypertension after subsequent nitric oxide withdrawal.


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