TITLE

Polymerase chain reaction is a good diagnostic tool for Mycobacterium tuberculosis in urine samples

AUTHOR(S)
Arisan, Serdar; Sönmez, N. Cem; Çakir, Ömer Onur; Ergenekon, Erbil
PUB. DATE
July 2003
SOURCE
Journal of Cell & Molecular Biology;2003, Vol. 2 Issue 2, p99
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Tuberculosis is a major public health problem in developing countries. Tuberculosis of the urinary tract is not uncommon in all over world, and it continues to be an important clinical problem, mainly because of its nonspecific clinical presentation and variable radiographic appearance, which often mimic other pathologic lesions. Detection of suspects bacterial population; direct smears can be used but they are often negative and do not differentiate tuberculosis from nontuberculous mycobacterium. Culture, which is more sensitive, takes 6 to 8 weeks because of the slow growth rate of mycobacterium. Polymerase chain reaction (PCR) is a technique used to amplify extremely small amounts of a specific genomic sequence rapidly. The presence of an extremely small number of bacteria can thus be detected within 24 to 48 hours. Therefore PCR is a promising tool for rapid detection of urinary tract tuberculosis in urine samples.
ACCESSION #
11166303

 

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