TITLE

Methanol regulated yeast promoters: production vehicles and toolbox for synthetic biology

AUTHOR(S)
Gasser, Brigitte; Steiger, Matthias G.; Mattanovich, Diethard
PUB. DATE
December 2015
SOURCE
Microbial Cell Factories;12/2/2015, Vol. 14, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Promoters are indispensable elements of a standardized parts collection for synthetic biology. Regulated promoters of a wide variety of well-defined induction ratios and expression strengths are highly interesting for many applications. Exemplarily, we discuss the application of published genome scale transcriptomics data for the primary selection of methanol inducible promoters of the yeast Pichia pastoris (Komagataella sp.). Such a promoter collection can serve as an excellent toolbox for cell and metabolic engineering, and for gene expression to produce heterologous proteins.
ACCESSION #
111387605

 

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